Musculoskeletal Diseases

438 trials 179 recruiting

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TociCCAre - Clinical trial evaluating tocilizumab for the treatment of chondrocalcinosis Pending

2024-515956-19-00 Chondrocalcinosis 5
Efficacy and safety of early intramuscular botulinum toxin injections in the prevention of shoulder deformity in infants with obstetric brac… Pending

2024-520391-10-01 Obstetrical Brachial Plexus Palsy 5
Repurposing Everolimus to enhance musculoskeletal Vitality and Ageing in The Elderly (RENOVATE) Pending

2023-509838-19-00 General healthy elderly with stable medical conditions 4
Assess effect and safety of intra-arterial autologous mesoangioblast administration to the upper arm of m.3243A>G mutation carriers Pending

2024-515129-27-00 m.3243A>G mutation causing mitochondrial myopathy 7
Anti-CD 19 CAR-T cell therapy in patients with ANCA Vasculitis - the IDEAL trial Pending

2024-517303-36-00 ANCA-IgG-positive ANCA associated vasculitis 9
Effects and health economic aspects of enzyme therapy in children and adults with Pompe disease Pending

2024-518269-92-00 Pompe disease / glycogenosis type II / acid maltase def 6
A Pilot, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Tolerability, Safety, and Pharmacokinetics of a Single Intra-art… Pending

2025-523737-26-00 Osteoarthritis of the knee 3
A Study of SGT-003 Gene Therapy in Duchenne Muscular Dystrophy Pending

2025-522949-22-00 Duchenne muscular dystrophy 5
Clinical and ultrasound assessment of the therapeutic response to ixekizumab in psoriatic arthritis dactlylitis; a multicentre, parallel-gro… Pending

2022-503119-40-00 psoriatic arthritis (PsA) 5
Efficacy, Safety, and Tolerability of DYNE-101 in Participants with Myotonic Dystrophy Type 1 Pending

2025-522957-20-00 Myotonic Dystrophy Type 1 5
Study comparing two dosing methods of tocilizumab in patients with rheumatoid arthritis in remission or with low disease activity Pending

2025-522319-41-00 rheumatoid arthritis 6
ZAMBA: Zoledronic Acid for Modic Back Pain. Pending

2024-517345-14-00 Low Back Pain 5
Role of Vitamin C at 6 Months on Incidence of Complex Regional Pain Syndrome Type I in Upper Limb Surgery (CRPS-VITC) Pending

2024-518310-28-00 Algoneurodystrophy CRPS type 1 5
Pregabalin or Baclofen in Spastic Motor Behavior Treatment After SCI (PoBSCI), Prospective, Double-Blind, Randomised Drug Study Pending

2024-518824-56-00 Complete to incomplete (AIS A-C) sub-acute cervical or 5
A trial to compare treatment with surlorian (ARM210, S48168) to placebo in effects on muscle strength and safety in adults with autosomal do… Pending

2025-522343-18-00 Autosomal Dominant RYR1-Related Myopathy 4
FAPI-PET for GPSD Pending

2024-511977-31-01 giant cell arteritis - polymyalgia rheumatica spectrum 4
Post-operative analgesia and spinal block duration following total hip arthroplasties Pending

2025-522358-38-02 Hip osteoarthrosis and postoperative pain 6
Evaluation of the clinical implementation of biofilm susceptibility to antibiotics using Minimum Biofilm Eradication Concentration (MBEC) in… Pending

2024-518350-17-00 Periprosthetic hip joint infection Periprosthetic knee 6
A Study to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ALE1 in Healthy Adults and Adults with Hypophosphatasia in … Pending

2025-522378-36-00 Hypophosphatasia 7
Adductor canal and IPACK (infiltration between the popliteal artery and the capsule of the knee) blocks versus genicular nerves block for to… Pending

2025-523071-34-00 Knee Osteoarthritis 6
Feasibility and Safety Assessment of a Combined Advanced Therapy Medicinal Product Based on A Polymeric Medical Device Combined to Autologou… Pending

2024-512977-28-01 Patients with knee femoral cartilage isolated lesions 1
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Global Study with an Open-Label Extension to Evaluate the Efficacy and Safety of In… Pending

2025-523087-20-00 Duchenne muscular dystrophy 5
Efficacy and safety of zoledronate versus placebo on pain at week 12 in pediatric patients with chronic recurrent multifocal osteomyelitis r… Pending

2023-506420-93-00 Chronic recurrent multifocal osteomyelitis (CRMO) 4
ATA-200 gene therapy trial in patients with LGMDR5 Pending

2023-506440-16-00 limb-girdle muscular dystrophy type R5 (previously name 7