Musculoskeletal Diseases

438 trials 179 recruiting

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A Phase 3, Long-Term Extension Study to Evaluate the Long-Term Safety, Tolerability, and Efficacy of Zasocitinib in Subjects with Active Pso… Pending

2025-522586-30-00 Psoriatic Arthritis 5
ATRIO Study: Effect of Romosozumab vs. Denosumab on Coronary Atherosclerotic Damage in Postmenopausal Osteoporosis: A Phase IV, Low-Risk Int… Pending

2025-522592-29-00 Coronary atherosclerotic status in women with postmenop 6
A randomized placebo controlled trial testing the effect of Zoledronic Acid on Hip osteoarthritis Pending

2025-521435-36-01 Osteoarthritis of the Hip 6
Influence Of Zoledronic Acid On Healing After Arthroskopic Repair Of Chronic Rotator Cuff Lesions A Prospective, Randomized, Placebo-Control… Pending

2024-519082-22-00 Trauma (rupture of a tendon) 4
An open label, randomized, multiple-dose, two-treatment, two-period, cross-over bioequivalence study comparing Pyridostigmine Bromide, P.R.T… Pending

2025-524219-35-00 treatment of myasthenia gravis 2
A clinical study of tulisokibart in people with psoriatic arthritis (MK-7240-015) Recruiting

2025-520997-21-00 Psoriatic arthritis 4 2026-05-08
Safety, tolerability, pharmacokinetics, and efficacy of filgotinib for the treatment of polyarticular-course juvenile idiopathic arthritis i… Recruiting

2024-511593-70-00 Polyarticular-course juvenile idiopathic arthritis 5 2026-04-27
A multi-centre, single-arm study to demonstrate the efficacy of bone marrow allogeneic mesenchymal cells combined with biomaterial (combined… Recruiting

2025-520841-60-00 Delayed consolidation or non-union long bone fracture 5 2026-04-24
A Study Comparing the Efficacy and Tolerability of a Triple Combination of Diclofenac, Orphenadrine and Paracetamol Versus Diclofenac Monoth… Recruiting

2025-521578-32-00 LOW BACK PAIN 5 2026-04-05
Pediatric Safety Follow-up Study of Prior Treatment with Romosozumab for Osteogenesis Imperfecta Recruiting

2023-503293-21-00 Osteogenesis Imperfecta 5 2026-03-25
A study to investigate safety, tolerability, pharmacokinetics, and pharmacodynamics of surovatamig in adult participants with rheumatoid art… Recruiting

2025-522273-10-00 Systemic Lupus Erythematosus 3 2026-02-24
A Global Phase 3 Open-Label Extension Study to Assess AOC 1001 in Patients with DM1 Recruiting

2025-520766-22-00 Myotonic Dystrophy Type 1 5 2026-01-21
Randomised, Multicentre, Multinational, Double-Blind Integrated Study to Compare the Pharmacokinetics, Efficacy, Safety, and Immunogenicity … Recruiting

2025-521562-95-00 Previously Untreated Advanced (Unresectable or Metastat 5 2025-12-30
A Study to Assess How Effective and Safe NVD003 is for Treating Patients with Congenital Pseudarthrosis of the Tibia. Recruiting

2025-520998-39-00 Congenital pseudarthrosis of the tibia 5 2025-11-07
Treatment of osteoarthritis behind the kneecap with tissue engineered nasal cartilage in a randomized, controlled, multicenter clinical tria… Recruiting

2023-508640-21-00 Patellofemoral osteoarthritis 4 2025-09-22
A Phase 2 Randomized Trial Evaluating Efficacy of AGA2118 in Postmenopausal Women with Low Bone Mass (ARTEMIS) Recruiting

2024-515610-41-00 Postmenopausal Osteoporosis 4 2025-09-11
A 2-Part, Randomized, Double-Blind, Placebo-Controlled Study in Participants with Duchenne Muscular Dystrophy Amenable to Exon 45 Skipping t… Recruiting

2024-517499-39-00 Duchenne Muscular Dystrophy 7 2025-07-16
A Study to Find Out How Nusinersen is Processed in the Body When Given Through the ThecaFlex DRx™ System in Adult and Pediatric Participants… Recruiting

2024-514239-21-00 Spinal Muscular Atrophy 3 2025-05-21
A Phase I, Open-Label Study of CLN-978 in Patients with Treatment-Refractory Rheumatoid Arthritis (RA) Recruiting

2024-519114-31-00 Treatment-Refractory Rheumatoid Arthritis 3 2025-05-15
3TR-PARTNER-RA Recruiting

2024-511470-79-00 Rheumatoid Arthritis 6 2025-02-11
Open-label, Phase 3 Gene Delivery Study with SRP-9003 in LGMD 2E/R4 Subjects Recruiting

2022-503112-17-00 Limb-girdle muscular dystrophy, type 2E/R4 (LGMD2E/R4) 5 2024-10-16
A Phase 2 Clinical Trial to Investigate Safety, Tolerability and Efficacy of TransCon CNP, Weekly Subcutaneous Injections, Compared with Pla… Recruiting

2023-506091-27-00 Achondroplasia in Children and Adolescents 4 2024-09-19
Metformin as maintenance therapy in bone sarcomas at high risk of relapse Recruiting

2024-515639-32-00 bone sarcoma 4 2024-07-30
A clinical study to assess if a new investigational medicinal product called JJP-1212 is safe, tolerable and able to induce a specific immun… Recruiting

2023-508661-33-00 Rheumatoid Arthritis 1 2024-05-29