Musculoskeletal Diseases

438 trials 179 recruiting

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Open-Label Extension of EDG-5506 in Participants with Becker Muscular Dystrophy Recruiting

2023-506231-15-00 Becker Muscular Dystrophy 4 2024-02-22
Setrusumab vs Bisphosphonates in Pediatric Subjects with Osteogenesis Imperfecta (Cosmic) Recruiting

2023-504196-24-00 osteogenesis imperfecta 5 2023-10-17
A Phase 3 program evaluating the effect of filgotinib in subjects with active axial spondyloarthritis Recruiting

2022-501354-10-01 axial spondyloarthritis 5 2023-06-21
Phase Ib study of the combination of regorafenib with conventional chemotherapy for the treatment of newly diagnosed patients with multimeta… Recruiting

2023-503322-39-00 Newly diagnosed patients with metastatic (other than lu 3 2023-06-16
A Phase 3 Study to Investigate the Efficacy and Safety of Brepocitinib in Adults with Dermatomyositis Recruiting

2022-500367-12-00 Dermatomyositis 5 2022-11-30
A prospective multicentre single-arm study in adults to evaluate the safety and preliminary efficacy of the autologous 3D osteogenic implant… Recruiting

2024-517762-42-01 recalcitrant lower limb nonunion 7 2018-08-02
Anti-B-cell therapy in RA-ILD Recruiting

2025-524872-51-00 Rheumatoid arthritis-associated interstitial lung disea 6 2026-05-25
A Phase IIb, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Intra-Articular Allocetra in Participants with Primary Knee… Recruiting

2025-524668-39-00 Knee Osteoarthritis 4 2026-05-15
A Phase 3 Trial Investigating the Efficacy and Safety of Weekly Lonapegsomatropin Compared to Daily Somatropin in Children with Short Statur… Recruiting

2025-523079-44-00 Turner Syndrome (TS) 5 2026-04-15
A Phase 3 Study to Evaluate AOC 1020 in Participants with FSHD Recruiting

2025-521012-18-00 Facioscapulohumeral Muscular Dystrophy (FSHD) 5 2026-04-13
A Phase 2a, Randomized, Double-Blind, Placebo-Controlled Dose Comparison and Exploratory Efficacy Study of Orally Administered SAT-3247 in A… Recruiting

2025-522522-13-01 Duchenne muscular dystrophy 4 2026-04-08
Not Applicable Recruiting

2024-511198-31-00 Lupus Nephritis 10 2026-03-24
Anesthetic block of the erector muscles of the lumbar spine to relieve acute lumbar pain: pilot study Recruiting

2024-511818-21-00 Acute law back pain 5 2026-03-06
Characterization of the immune response in immunosuppressed patients with rheumatic diseases, including to the recombinant zoster vaccine Recruiting

2024-518190-34-00 rheumatic disease 6 2026-02-16
RANDOMISED, MULTICENTRE, DOUBLE-BLIND CLINICAL TRIAL TO EVALUATE THE EFFICACY AND SAFETY OF MONTELUKAST VS. PLACEBO IN PATIENTS WITH EROSIVE… Recruiting

2025-521802-17-00 Erosive/inflammatory osteoarthritis of the hands 5 2026-01-30
A study to investigate the safety and efficacy of infigratinib compared with placebo in infants and young children with achondroplasia Recruiting

2024-518072-31-00 Achondroplasia 4 2026-01-27
A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the Knee ( ATTAIN-OA PAIN ) Recruiting

2025-522631-34-00 Osteoarthritis 5 2026-01-14
RANDOMISED CLINICAL STUDY TO ASSESS THE EFFICACY AND SAFETY OF PLATELET-RICH PLASMA (PRP) INFILTRATION COMBINED WITH PHYSICAL EXERCISE IN CH… Recruiting

2025-522700-24-00 CHRONIC OMALGIA 5 2026-01-13
Frozen shoulder – can physiotherapy improve the outcome? Recruiting

2024-519728-26-00 Frozen shoulder 6 2026-01-12
A phase I, prospective, mono-center, double-blinded, randomized, controlled study to assess the safety and tolerability of intraarticular in… Recruiting

2024-517421-12-00 Osteoarthritis 3 2026-01-07
Ketoanalogue Supplementation for Muscle Protection in chronic kidney disease (stade 4 and 5) Patients with Moderately Low Protein Diet Recruiting

2024-516764-29-00 kidney disease 5 2026-01-05
A Phase 1b open label pilot study of CLN-978 for the treatment of moderate to severe systemic lupus erythematosus (SLE) Recruiting

2024-518780-36-00 Systemic Lupus Erythematosus 3 2025-12-10
RHIBOT II - Medium- and long-term efficacy of two ultrasound-guided intra-articular injections of onabotulinumtoxinA (Botox®) combined with … Recruiting

2024-515028-35-00 Adults aged at least 18 years with painful base-of-thum 5 2025-12-03
Phase 3 Study of Dotinurad vs Allopurinol in Participants With Gout Recruiting

2024-520206-19-00 Hyperuricemia associated with gout. 5 2025-12-02