Nervous System Diseases

1,005 trials 421 recruiting

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Efficacy of Ketamine for the Prevention of Relapse in Patients with Opioid-Use Disorders (OUD) Pending

2025-520843-34-00 Opioid Use Disorder 4
CACH RECEVA: Calcium Channel blocker in treatment of reversible cerebral vasoconstriction syndrome: a double-blind, randomized, placebo-cont… Pending

2023-504547-14-01 Reversible cerebral vasoconstriction syndrome 6
HiHat trial Pending

2024-519700-28-01 Patients with relapsing-remitting multiple sclerosis wi 4
StroKE34 Study Protocol: a randomized Controlled Phase IIa trial of intra-arterial Cd34+ Cells in acute ischemic Stroke Pending

2025-520850-13-00 Ischemic Stroke 4
Patient Evaluation of OraFID, a New Medicine Dispenser and App for Flexilev minitablets Pending

2025-524296-23-01 Parkinsons Disease 6
APICALE - Cervical facet injection of corticosteroids for the management of cervicobrachialgia : protocol for a randomized pilot study Pending

2024-511790-30-00 Cervicobrachial Neuralgia 5
Efficacy of probenecid on cluster seizures during dosage reduction of Anti Seizure Medication (ASM) in presurgical focal epilepsy video-EEG … Pending

2024-519133-29-00 Focal epilepsy 4
MEDICAL CANNABIS TREATMENT IN NEURODEGENERATIVE DISEASES (NEUROBIS) Pending

2023-507715-35-02 Patients suffering from neurodegenerative diseases: Amy 4
Proof-of-Concept Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy Study of Intranasal Cenegermin in Adult Participants … Pending

2025-522692-29-00 Subacute Moderate to Severe Traumatic Brain Injury (TBI 4
Reduction of SystemiC Inflammation after ischemic stroke by intravenous DNase administration (ReSCInD) Pending

2024-516701-22-00 Reduction of SystemiC Inflammation after ischemic strok 4
uPAR PET/MRI in glioma Pending

2024-519723-20-01 Glioma 9
Dexamethasone for the treatment of traumatic brain injured patients with brain contusions and pericontusional edema: Study protocol for a pr… Pending

2025-520887-17-00 Post-traumatic brain contusion with edema 6
A Phase 1/2 Study of the Safety and Tolerability of ICM VTx-002 in participants with ALS Pending

2025-522697-37-00 Amyotrophic Lateral Sclerosis 7
A Phase 3 Study of Orelabrutinib in Patients with Primary Progressive Multiple Sclerosis Pending

2025-524316-11-00 Primary Progressive Multiple Sclerosis (PPMS) 5
EFFECTS OF SAFINAMIDE VERSUS PLACEBO ON PAIN IN PATIENTS WITH PARKINSON’S DISEASE WITH MOTOR FLUCTUATIONS: A RANDOMIZED, CONTROLLED, DOUBLE-… Pending

2025-521512-20-00 PARKINSON’S DISEASE WITH MOTOR FLUCTUATIONS 5
Open-Label Extension Study to Provide Access to ATH434 in Patients with Multiple System Atrophy Pending

2025-524317-88-00 Multiple System Atrophy 4
A Phase III, randomized, placebo-controlled, parallel group, double-blind study to evaluate the efficacy and safety of NIO752 in participant… Pending

2025-523481-24-00 Participants with Progressive Supranuclear Palsy Richar 5
A Phase 2 Study of NEU-411 in Companion Diagnostic-Positive Participants with Early Parkinson’s Disease Pending

2024-515448-22-00 Parkinson 4
Upper-limb Active Function and Botulinum Toxin A Pending

2024-518147-37-00 Stroke 4
Pilot study of the efficacy of nicotinamide (vitamin B3) in Leber's hereditary optic neuropathy - NICOLHON Pending

2025-524343-13-00 Leber's Hereditary Optic Neuropathy 4
Open label safety study of tasimelteon indicated in the treatment of blind individuals with no light perception having problems synchronizin… Pending

2024-516721-31-00 Non-24 Hour Sleep-Wake Disorder 5
Chronic CandClus2: A randomized, placebo-controlled, triple blind crossover study of candesartan in adults with chronic cluster headache Pending

2025-521529-34-00 chronic cluster headache 5
Extension Study of ACT-EARLY Pending

2024-513676-18-00 Transthyretin Amyloidosis 5
A Study of Treatments for the Prevention of Disease Progression in Individuals at Risk for or With Early Onset Alzheimer’s Disease Caused by… Pending

2024-517187-36-01 Dominantly Inherited Alzheimer’s Disease (DIAD) 10