Nervous System Diseases

1,005 trials 421 recruiting

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CITADEL: a study to asess the effectiveness of CITicoline (TRAUSAN) in preventing cognitive decline After DELirium in older adults with prox… Pending

2025-522306-21-00 Cognitive profiles 4
A PHASE 1B, MULTICENTER, RANDOMIZED, PLACEBO- CONTROLLED, DOUBLE-BLIND STUDY TO EVALUATE THE SAFETY, TOLERABILITY, AND BIOLOGICAL ACTIVITY O… Pending

2023-504746-54-00 AMYOTROPHIC LATERAL SCLEROSIS 3
Efficacy, Safety, and Tolerability of DYNE-101 in Participants with Myotonic Dystrophy Type 1 Pending

2025-522957-20-00 Myotonic Dystrophy Type 1 5
A Clinical Trial to Investigate the Efficacy, Safety and Pharmacokinetics of Elsunersen in Children Pending

2024-515598-82-00 Voltage-gated sodium channel type II alpha subunit (SCN 5
Effect of Sildenafil in association to Hypothermia on survival without brain lesions In term Neonates with hypoxic-ischemic Encephalopathy: … Pending

2023-508928-35-00 Hypoxic ischemic encephalopathy 10
A randomized, double-blind, placebo-controlled, single-ascending-dose study in healthy volunteers and a double-blind, placebo-controlled, mu… Pending

2024-513411-27-00 Parkinson’s disease 1
Comparison of two treatments (intrathecal baclofen pump and selective dorsal rhizotomy) for children with cerebral palsy who cannot walk Pending

2024-518822-33-01 Cerebral Palsy 6
Prevention of chronic headache with anti-CGRP antibody treatment in patients with idiopathic intracranial hypertension Pending

2025-524822-16-00 Idiopathic intracranial hypertension 5
Pregabalin or Baclofen in Spastic Motor Behavior Treatment After SCI (PoBSCI), Prospective, Double-Blind, Randomised Drug Study Pending

2024-518824-56-00 Complete to incomplete (AIS A-C) sub-acute cervical or 5
ACUMEN: Acute High Dose Melatonin for Encephalopathy of the Newborn Pending

2025-520538-49-00 Moderate-Severe Hypoxic-Ischaemic Encephalopathy (HIE) 1
Complement Inhibition: Attacking the Overshooting Inflammation @fter Subarachnoid Hemorrhage Pending

2025-520540-15-00 aneurysmal subarachnoid hemorrhage 4
A pivotal study of N-Acetyl-L-Leucine on CACNA1A Disorders Pending

2025-523828-51-00 CACNA1A Disorders 5
A clinical trial to assess the safety of EXV-802 and EXV-801 and how well they work to reduce agitation symptoms in people with Alzheimer's … Pending

2024-517388-22-00 Agitation in Alzheimer's Disease Dementia 10
Comparison of iodinated contrast media injection protocols with reduced flow rates and volumes on image quality in diagnostic cerebral angio… Pending

2025-524884-18-01 Intracranial aneurysms 5
A double-blind, randomised, placebo-controlled, first-in-human (FIH) Phase I/IIa, multi-centre trial to assess safety, tolerability, and imm… Pending

2024-515627-10-00 generalised myasthenia gravis 7
A study to evaluate the safety and tolerability of TTX-381 in participants with ocular manifestations of CLN2 disease Pending

2025-521175-31-00 Ocular manifestations of Neuronal Ceroid Lipofuscinosis 7
Continous fentanyl infusion in newborns with hypoxic ischemic encephalopathy treated with therapeutic hypothermia: pharmacokinetics study Pending

2024-516076-15-00 Infants with perinatal asphyxiation and indication to h 3
Extending the time window for Tenecteplase by Effective RecanalizatioN of bAsilar artery occLusion in patients with POSTerior circulation st… Pending

2024-513444-28-00 Acute ischaemic stroke due to basilar artery occlusion. 5
Methylphenidate for Early Awakening in Coma (MEAWAKE) Pending

2025-524937-19-00 Coma due to acute brain injury 4
Phase I/II combination umbrella trial in progressive/relapsed/refractory pediatric low-grade glioma (pLGG) (EPILOGUE) Pending

2024-516896-34-00 progressive/relapsed/refractory pediatric low-grade gli 9
Evaluation of [18F]MC225 to measure P-glycoprotein function in neurodegenerative disease Pending

2024-518865-85-00 Alzheimers Disease 4
SPN-817 Phase 2, Double-Blind, Placebo-Controlled Study in Adults with Focal Onset Seizures Pending

2025-520587-18-00 Focal Onset Seizures 4
Nordic PREdnisolon for VEstibular NeuriTis Study – an investigator-driven, triple blind, placebo controlled randomized trial Pending

2025-522399-10-00 Vestibular neuritis 5
MECHANISMS OF NEURONAL RESILIENCE IN ALZHEIMER'S DISEASE AND ITS FOCAL VARIANTS: A MRI/TEP STUDY Pending

2024-519995-20-00 Maladie d' Alzheimer 10