Nervous System Diseases

1,005 trials 421 recruiting

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Efficacy and Safety of Cariprazine in the Treatment of Adolescent Participants (13 to 17 years of age) with Schizophrenia Ended

2024-513194-44-00 Adolescent Patients (13 to 17 years of age) with Schizo 5 2021-12-14
Randomised, double-blind, placebo-controlled study to evaluate the effect of metformin, an AMPK activator, on cognitive measures of progress… Ended

2024-518875-73-00 Huntington Disease 5 2021-12-10
A Study of LY3372689 to Assess the Safety, Tolerability, and Efficacy in Participants With Alzheimer’s Disease Ended

2024-512295-36-00 Alzheimer Disease 4 2021-12-06
A study to investigate the safety and efficacy of AMX0035 in patients with Amyotrophic Lateral Sclerosis Ended

2023-508511-23-00 Amyotrophic Lateral Sclerosis (ALS) 5 2021-12-02
FINISHER – Fight INflammation to Improve outcome after aneurysmal Subarachnoid HEmorRhage Ended

2024-512314-17-00 Aneurysmal Subarachnoid Hemorrhage (SAH) 5 2021-11-24
A Study to Compare the Safety and Efficacy of Dysport® and Botox® in Adults with Upper Limb Spasticity Ended

2023-509196-16-00 Upper limb spasticity (ULS) of any aetiology (in US and 6 2021-11-19
A Study to Evaluate B Cell Levels in Infants Potentially Exposed to Ocrelizumab During Pregnancy - The MINORE Study Ended

2024-510974-25-00 Multiple Sclerosis (MS) or Clinically Isolated Syndrome 6 2021-11-10
A study to learn if bepranemab is safe and works in people with early stages of Alzheimer’s Disease Ended

2023-506170-12-00 Alzheimer’s Disease 4 2021-10-18
Proof-of-concept study for SAR445088 in chronic inflammatory demyelinating polyneuropathy (CIDP) Ended

2024-512345-16-00 Chronic inflammatory demyelinating polyradiculoneuropat 4 2021-10-13
Adjuvant dendritic cell immunotherapy complementing conventional therapy for pediatric patients with high-grade glioma and diffuse intrinsic… Ended

2024-515295-12-00 High-grade glioma (HGG) 4 2021-10-06
Efficacy of Tocilizumab in association to steroids in giant cell arteritis with cerebro-vascular involvement patients (ToGiAS). A french pro… Ended

2024-511906-21-00 Giant cell arteritis with Cerebro-vascular involvement 5 2021-09-24
Phase 3 Open label clinical trial with oral Atogepant for the prevention of migraine Ended

2023-507096-21-00 Chronic or Episodic Migraine (Migraine without aura, mi 5 2021-08-16
Study of efficacy and tolerability of ofatumumab vs. First Line disease modifying treatment (DMT) - physician’s choice in the treatment of n… Ended

2023-507431-37-00 relapsing multiple sclerosis (RMS) 5 2021-07-23
Eptinezumab as Preventive Treatment of Migraine in Adults with Migraine Ended

2023-510183-12-00 Chronic migraine 5 2021-07-05
Lighthouse II study Ended

2024-517054-94-00 AMYOTROPHIC LATERAL SCLEROSIS 5 2021-07-05
HOPE study Ended

2024-516642-19-01 Acute Ischemic Stroke 6 2021-06-16
Guanabenz in VWM Ended

2023-503320-89-00 Vanishing White Matter 9 2021-05-31
A clinical trial which runs in multiple countries and aims to evaluate the long-term safety and tolerability of the investigational product … Ended

2024-512123-37-00 Parkinson's disease 5 2021-05-27
A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE Plus) Ended

2023-506918-45-00 Mild cognitive impairment (MCI) or mild dementia, both 5 2021-05-17
A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE) Ended

2023-506919-18-00 Mild cognitive impairment (MCI) or mild dementia, both 5 2021-05-17
Assessment of the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's … Ended

2023-504991-31-00 Agitation in Patients With Dementia of the Alzheimer's 5 2021-05-06
A Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter Study with a Long-Term Extension Treatment Period to Assess the … Ended

2022-501188-42-00 Early Alzheimer's Disease 4 2021-04-15
Assessment of the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's … Ended

2023-504990-19-00 Agitation in Patients With Dementia of the Alzheimer's 5 2021-04-06
A study to learn if lacosamide is safe to take over a long period of time in children with epilepsy Ended

2022-502639-21-00 Epilepsy 5 2020-12-28