Nervous System Diseases

1,005 trials 421 recruiting

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A study investigating the pain-relieving effects of a new drug in healthy adults Ended

2022-501804-80-00 Acute and chronic neuropathic pain secondary to diabeti 3 2022-11-17
Detect GHB Ended

2022-501329-18-00 Intoxication 11 2022-11-08
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Design, Prospective, 52-Week, Phase 2 Clinical Study to Evaluate the S… Ended

2024-511610-20-00 Alzheimer's Disease 4 2022-11-08
Bioequivalence of Oxazepam 10 mg Orodispersible Tablets Versus Seresta® 10 mg Tablets in Healthy Subjects Ended

2022-501134-35-00 No medical condition is being investigated. This is a c 2 2022-10-26
A phase 2/3 study to evaluate efficacy and clinical benefit of AT-007 with Sorbitol Dehydrogenase (SORD) Deficiency Ended

2024-518250-16-00 Sorbitol Dehydrogenase (SORD) Deficiency 10 2022-10-20
A Clinical Study to Assess the Safety, Tolerability of JNJ-63733657 and to evaluate how fast and to what extent JNJ-63733657 reaches the blo… Ended

2024-513656-15-00 Alzheimer's Disease (Healthy Participants) 3 2022-10-17
A clinical study to investigate the efficacy and safety of NT 201 in the treatment of lower limb spasticity in children and adolescents with… Ended

2023-503420-19-00 Pediatric lower limb (LL) spasticity (SP) caused by cer 5 2022-10-12
A study to find out how healthy people tolerate a new drug called S221237. Ended

2024-519381-53-00 Parkinson disease (PD) 1 2022-10-04
A Phase 3 study to determine the Efficacy and Safety of Losmapimod in Treating Patients with Facioscapulohumeral Muscular Dystrophy (REACH) Ended

2024-512737-33-00 Facioscapulohumeral Muscular Dystrophy (FSHD) 5 2022-09-30
Dual action weight loss in IIH - IIHDUAL Ended

2024-517120-19-02 Idiopathic Intracranial Hypertension 6 2022-09-02
A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7486967 in Participants with Early Idiopathic Pa… Ended

2023-504412-14-00 Early Idiopathic Parkinson’s Disease (PD) 3 2022-09-01
A Study of Eptinezumab in Participants With Migraine and Medication Overuse Headache Ended

2024-510729-24-00 Chronic Migrane, Migrane, Medication Overuse Headache 6 2022-09-01
Clemastine fumarate as remyelinating treatment in internuclear ophthalmoparesis and multiple sclerosis Ended

2024-513099-17-00 Internuclear ophthalmoparesis 5 2022-08-30
Evaluation of the efficacy of intra venous dornase alfa (Pulmozyme®) on arterial recanalization in post-thrombectomy angiography in patients… Ended

2024-515831-31-00 Ischemic stroke 4 2022-08-19
Regorafenib in combination with temozolomide with or without radiotherapy in patients with newly diagnosed MGMT-Methylated, IDH wild-type gl… Ended

2024-514424-16-00 MGMT-Methylated, IDH wild-type glioblastoma 3 2022-07-04
Iron chelation in the prevention of secondary degeneration after stroke Ended

2024-514230-20-00 Stroke 4 2022-06-08
Evaluation de l’efficacité des alpha-bloquants (Tamsulosine) dans le traitement de la dysurie symptomatique de la sclérose en plaques chez l… Ended

2024-516880-10-00 Patiente atteinte de sclérose en plaques (score EDSS < 4 2022-06-08
Evaluation of the Efficacy of Diclofenac Potassium and Rimegepant for the Acute Treatment of Migraine (ATOM) Ended

2024-517128-21-02 Migraine 6 2022-05-04
Open-label extesnion study of soticlestat in Dravet and Lennox-Gastaut Syndromes Ended

2022-502802-34-00 Dravet and Lennox-Gastaut Syndromes 5 2022-04-05
A Study to Investigate the Pharmacokinetics, Pharmacodynamics, Safety and Radiological and Clinical Effects of Subcutaneous (SC) Ocrelizumab… Ended

2023-505975-54-00 Multiple Sclerosis (MS) 5 2022-03-28
A study to learn if brivaracetam works and is safe in children and young adults 2 to 25 years of age with childhood absence epilepsy or juve… Ended

2023-510428-55-00 Childhood Absence Epilepsy Juvenile Absence Epilepsy 10 2022-03-10
MR-Spectroscopy: Investigating neurochemical changes in brain metabolism in migraineurs before and after CGRP-Antibody treatment – a randomi… Ended

2024-517079-19-00 migraine 6 2022-02-21
Short-term effectiveness of Gabapentin versus Placebo in acute Lumbosacral Radiculalgia by herniation disc: a prospective, multicentric, ran… Ended

2024-518053-42-00 lumbosacral radiculalgia 6 2022-02-09
A Phase 2a study to evaluate, safety, tolerability, pharmacodynamic markers, and pharmacokinetics of AP-101 in patients with amyotrophic lat… Ended

2024-512343-23-00 Amyotrophic Lateral Sclerosis (ALS) 4 2022-01-12