A study to learn how zilucoplan moves throughout the body over time when given in 2 different ways in healthy adults

2023-508388-64-00 Protocol DV0012 Human pharmacology (Phase I) - Bioequivalence study Ended

Start 5 Aug 2024 · End 26 Nov 2024 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol DV0012

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Bioequivalence study
Status Ended
Participants planned 14
Countries 1
Sites 1

Healthy Volunteers

Key facts

Sponsor
UCB Biopharma
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Male and Female
Therapeutic area
Phenomena and Processes [G] - Musculoskeletal and Neural Physiological Phenomena [G11]
Trial duration
5 Aug 2024 → 26 Nov 2024
Decision date (initial)
2024-06-12
Transition trial
No
Low-intervention
No
Rare-disease indication
Yes
Vulnerable population
No

External identifiers

EU CT number
2023-508388-64-00
WHO UTN
U1111-1303-7028

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Healthy Volunteers

VersionLevelCodeTermSystem organ class
26.0 LLT 10088820 Clinical trial healthy volunteer 100000004848

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

UCB Biopharma

Sponsor organisation
UCB Biopharma
Address
Researchdreef 60
City
Anderlecht
Postcode
1070
Country
Belgium

Scientific contact point

Organisation
UCB Biopharma
Contact name
UCB Cares

Public contact point

Organisation
UCB Biopharma
Contact name
UCB Cares

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Netherlands Ended 14 1
Rest of world 0

Investigational sites

Netherlands

1 site · Ended
Pharmaceutical Research Associates Group B.V.
#001_00270428: Program Management, Van Swietenlaan 6, 9728 NZ, Groningen

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Netherlands 2024-08-05 2024-11-26 2024-08-05 2024-08-23

Results and documents

Annex IV summary of results, Annex V layperson summary, and all documents registered in CTIS for this trial

Documents 1 file

Public protocol annexes, IB summaries, regulatory submissions and post-authorisation documents registered in CTIS.

TypeTitleVersion
Clinical study report (for publication) dv0012-csr-final-CTIS-public NA

Application history

3 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-04-10 Netherlands Acceptable
2024-06-12
2024-06-12
2 NON SUBSTANTIAL MODIFICATION NSM-1 2024-10-23 Netherlands Acceptable
2024-06-12
2024-10-23
3 NON SUBSTANTIAL MODIFICATION NSM-2 2024-12-03 Netherlands Acceptable
2024-06-12
2024-12-03