Open-label, randomized, two-treatment, two-period, two-sequence, cross-over, single dose, bioequivalence study comparing ISOPRINOSINE® FORTE 100 mg/mL Syrup to ISOPRINOSINE® 500 mg tablets in healthy male and female subjects under fasting conditions.

2024-514146-37-00 Protocol EWO-ISO-2024/BE2 Human pharmacology (Phase I) - Bioequivalence study Ended

Start 24 Oct 2024 · End 21 Nov 2024 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol EWO-ISO-2024/BE2

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Bioequivalence study
Status Ended
Participants planned 36
Countries 1
Sites 1

not applicable (submitted trial is a bioequivalence study)

Key facts

Sponsor
Ewopharma AG
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Male and Female
Therapeutic area
Diseases [C] - Virus Diseases [C02]
Trial duration
24 Oct 2024 → 21 Nov 2024
Decision date (initial)
2024-09-06
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
Yes

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

not applicable (submitted trial is a bioequivalence study)

VersionLevelCodeTermSystem organ class
21.1 PT 10068724 Antiviral treatment 100000004865
20.1 PT 10007877 Cell-mediated immune deficiency 100000004870

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Ewopharma AG

Sponsor organisation
Ewopharma AG
Address
Vordergasse 43
City
Schaffhausen
Postcode
8200
Country
Switzerland

Scientific contact point

Organisation
Ewopharma AG
Contact name
Suzanne Curran

Public contact point

Organisation
Ewopharma AG
Contact name
Suzanne Curran

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Czechia Ended 36 1
Rest of world 0

Investigational sites

Czechia

1 site · Ended
Quinta-Analytica s.r.o.
Clinic, Umelecka 305/1, Moravska Ostrava, Moravska Ostrava A Privoz

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Czechia 2024-10-24 2024-11-21 2024-10-24 2024-11-13

Application history

1 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-08-09 Czechia Acceptable
2024-09-03
2024-09-06