Ifosfamide — Drug Intelligence | 38 EU Trials

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38 Registered trials

20 Recruiting

15 Completed trials

28 Sponsors

21 Countries

Phase III

Phase II

Phase I/II

Phase III: 18 Phase II/III: 3 Phase II: 11 Phase I/II: 4 Phase IV: 1 Phase I (Other): 1

Oversight events:

1 serious breach 2 unexpected events across 2 trials

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Indications tested

Ewing's sarcoma 2 Diffuse large B-cell lymphoma 2 Neuroblastoma 2 Extra-osseous Ewing's sarcoma recurrent 1 High-grade B-cell lymphoma 1 Primary mediastinal large B-cell lymphoma 1 Adult T-cell lymphoma/leukaemia 1 Burkitt's lymphoma 1 Extra-osseous Ewing's sarcoma 1 Head and neck cancer 1 Non-Hodgkin's lymphoma unspecified histology aggressive recurrent 1 Testicular seminoma (pure) 1

Sponsors using this IMP

GPOH gGmbH 3 The University Of Birmingham 3 Unicancer 3 Institut Bergonie 2 Kite Pharma Inc. 2 Universitaetsklinikum Muenster AöR 2 University Of Cologne 2 Charite Universitaetsmedizin Berlin KöR 1 European Organisation For Research And Treatment Of Cancer 1 Europese Organisatie Voor Onderzoek En Behandeling Van Kanker Organisation Europeenne Pour La Recherche Et Le Traitement Du Cancer European Organi 1 F. Hoffmann-La Roche AG 1 Fondazione IRCCS Istituto Nazionale Dei Tumori 1

All trials

38 total

IntReALL BCP 2020 – International Study for Treatment of Childhood Relapsed Precursor B-cell ALL 2020 Pending

2023-509392-17-00 Phase III 11 countries Charite Universitaetsmedizin Berlin KöR
Prospective multicenter clinical trial for risk estimation and treatment stratification in low and intermediate risk neuroblastoma patients … Pending

2024-517295-37-00 Phase III 1 country University Of Cologne
Phase II Prospective Multicenter Study of High-Dose Treosulfan/Melphalan as Consolidation Treatment in Newly Diagnosed High-Risk and Very Hi… Pending

2024-518912-37-01 Phase II 1 country Fondazione Santobono Pausilipon Onlus
International open-label phase I dose escalation study of dinutuximab beta in combination with vincristine/doxorubicin/cyclophosphamide and … Recruiting

2024-515245-42-00 Phase I (Other) 4 countries GPOH gGmbH
A trial to learn how effective and safe odronextamab is compared to standard of care for adult participants with previously treated aggressi… Recruiting

2022-502783-21-00 Phase III 10 countries Regeneron Pharmaceuticals Inc.
A study to test the effect of chemotherapy before surgery compared to surgery alone in patients with high risk retroperitoneal sarcoma. Recruiting

2023-505261-84-00 Phase III 10 countries European Organisation For Research And Treatment Of Cancer
Glo-BNHL: A Global Study of Novel Agents in Paediatric and Adolescent Relapsed and Refractory B-cell Non-Hodgkin Lymphoma Recruiting

2024-510575-38-00 Phase II/III 6 countries The University Of Birmingham
Phase Ib study combining dinutuximab beta with induction chemotherapy regimens in patients with newly diagnosed high-risk neuroblastoma Recruiting

2023-509673-22-00 Phase I/II 7 countries Prinses Maxima Centrum voor Kinderoncologie B.V.
Single-arm interventional study with ruxolitinib and AIEOP-BFM 2017 Poland or AIEOP-BFM 2017 standard of care chemotherapy in children with … Recruiting

2024-518316-39-00 Phase II/III 1 country Medical University Of Lodz
The Effect of Cancer Treatments on Speech Perception in Noise, Cognition, and Quality of Life Recruiting

2024-513437-21-00 Phase IV 1 country Turku University Hospital
Immunotherapy with dostarlimab for locally advanced or metastatic cancer (non-colorectal/non-endometrial) with tumor dMMR/MSI Recruiting

2023-505298-34-00 Phase II 1 country Unicancer
A prospective program aiming at improving outcome for young adults with poor-prognosis non seminomatous germ-cell tumors (VAPOR (GETUG T06)) Recruiting

2023-505040-19-00 Phase II 1 country Institut Gustave Roussy
A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Anti-Tumor Activity of Glofitamab in Monotherapy and in Combination with Che… Recruiting

2023-504264-41-00 Phase I/II 8 countries F. Hoffmann-La Roche AG
International Euro Ewing (iEuroEwing) trial for treatment optimisation in patients with Ewing sarcoma Recruiting

2022-501180-40-00 Phase III 8 countries GPOH gGmbH
Sequential neoadjuvant ifosfamide and doxorubicin in localized high-grade soft tissue sarcoma of extremities and trunk wall Recruiting

2023-510185-27-00 Phase II 1 country Oslo University Hospital HF
Interest of peri operative CHemotherapy In patients with CINSARC highrisk localized Soft Tissue Sarcoma. Recruiting

2024-515384-62-00 Phase III 1 country Oncopole Claudius Regaud
FaR-RMS: An overarching study for children and adults with Frontline and Relapsed RhabdoMyoSarcoma Recruiting

2024-510579-40-00 Phase I/II 16 countries The University Of Birmingham
An international trial for children with atypical teratoid/rhabdoid tumours (ATRT) Recruiting

2022-501456-28-00 Phase III 12 countries GPOH gGmbH
LBL 2018 - International cooperative treatment protocol for children and adolescents with lymphoblastic lymphoma Recruiting

2023-508101-24-00 Phase III 14 countries Universitaetsklinikum Muenster AöR
PHASE III TRIAL INVESTIGATING BENEFIT OF INTENSIFIED PERI-OPERATIVE CHEMOTHERAPY WITHIN HIGH-RISK CINSARC PATIENTS WITH RESECTABLE SOFT-TISS… Recruiting

2023-509489-39-00 Phase III 1 country Institut Bergonie
Randomised trial evaluating mifamurtide in combination with standard chemotherapy in patients with high-grade osteosarcoma at high risk of r… Recruiting

2024-514780-26-00 Phase II 1 country Unicancer
Evaluation of Lymphadenectomy and Chemotherapy TIP (paclitaxel, ifosfamide and cisplatin) on Inguinal Lymph Nodes in Squamous Cell Carcinoma… Recruiting

2024-512827-36-00 Phase II 1 country Unicancer
rEECur: International Randomised Controlled Trial of Chemotherapy for the Treatment of Recurrent and Primary Refractory Ewing Sarcoma Recruiting

2024-516078-31-00 Phase II/III 10 countries The University Of Birmingham
Pembro-CORE pilot Ended

2022-501306-35-00 Phase II 1 country University Of Cologne

Showing 1–24 of 38 trials

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