Phase I/II – First Administration

443 trials 187 recruiting

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Phase I/Ib clinical trial of PM54 in Advance Solid Tumors patients Recruiting

2023-508644-22-00 Advance Solid Tumors 2023-02-28
Phase I trial evaluating the tolerance of repeated opening of the bloodbrain barrier by ultrasound before chemotherapy in the treatment of r… Recruiting

2024-516169-35-00 recurrent primary supratentorial malignant brain tumors 2023-02-06
A modular, first time in human, open label, multiple dose, accelerated escalation with cohort expansion study of the safety and pharmacokine… Recruiting

2023-506818-45-00 Solid tumors that have a high incidence of Homologous R 2022-12-13
A phase 1/2a, open-label trial to investigate the safety, tolerability, pharmacokinetics, and pharmacodynamics of multiple ascending doses o… Recruiting

2024-514328-18-00 Spinocerebellar ataxia types 1, 3 and Huntington's dise 2022-12-06
A multicenter phase 1/2 study of OSE-279, a PD-1 blocking monoclonal antibody, in subjects with advanced solid tumors or lymphomas Recruiting

2024-514826-22-00 Part A: Patients with advanced solid tumors or lymphoma 2022-12-05
Phase I Study of PM534 Administered to Patients with Advanced Solid Tumors Recruiting

2024-513056-15-00 Advanced Solid Tumors 2022-12-01
A Phase 1/2 Study of the Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor NVL-655 in Patients with Advanced NSCLC and Other Solid Tumors… Recruiting

2024-514266-39-00 Advanced Non-Small Cell Lung Cancer (NSCLC) and Other S 2022-11-03
Clinical trial of infusion of activated NK cells for the treatment of children, adolescents and young adults with sarcomas. Recruiting

2024-513431-25-00 Sarcomas 2022-10-18
Study of AZD9574 as monotherapy and in combination with anti-cancer agents in patients with advanced solid malignancies Recruiting

2023-504984-17-00 Module 3: advanced/relapsed HER2-negative breast, ovari 2022-10-05
Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C) Recruiting

2022-502756-31-00 KRAS G12C-Mutant Advanced Solid Tumors 2022-07-20
A Phase 1/2 Study of BMS-986340 with and without Nivolumab or Docetaxel in Solid Tumors Recruiting

2023-503651-10-00 Male and female participants ≥ 18 years of age with adv 2022-05-17
Phase 1/2 study of IMC-M113V in virologically suppressed chronic HIV infection Recruiting

2024-513938-38-00 Chronic HIV infection 2022-04-06
A randomised, double blind clinical trial investigating the safety and tolerability of multiple increasing doses of EDV2209 compared to plac… Recruiting

2024-514590-22-00 Subarachnoid haemorrhage – SAH 2022-03-10
A Phase 1/2 Study of the Highly Selective ROS1 Inhibitor NVL-520 in Patients with Advanced NSCLC and Other Solid Tumors (ARROS-1) Recruiting

2024-511793-71-00 Advanced ROS1-positive NSCLC and other advanced ROS1-po 2022-02-28
Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-101 in Participants with Myotonic Dystrophy Type 1 Recruiting

2023-510353-42-00 Myotonic Dystrophy Type 1 2022-02-21
DZR123 (CPI-0209) in Patients with Advanced Solid Tumors and Lymphomas Recruiting

2023-508002-20-00 advanced, solid, relapsed tumors / advanced tumors: hum 2021-10-21
A Phase 1/2a, First-in-human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of HDP-101 in Patients with Plasma C… Recruiting

2024-515273-10-00 Relapsed or refractory Multiple Myeloma (r/r MM) 2021-10-19
A Phase 1/2 Trial of the Synthetic Cannabinoid ART27.13 in Patients with Cancer Anorexia and Weight Loss Recruiting

2024-518177-33-00 Cancer Anorexia 2021-10-01
An early phase clinical trial to investigate EO2463, a novel cancer vaccine therapy, in patients with indolent Non-Hodgkin's Lymphoma. Recruiting

2023-509254-58-00 Indolent Non-Hodgkin's Lymphoma (Follicular Lymphoma; M 2021-05-31
A study investigating single injection of new botulinum toxin to determine safety and efficacy for treating spasticity in the upper limb Recruiting

2023-507202-14-00 Upper limb spasticity after stroke or traumatic brain i 2021-04-29
A clinical study in 3 parts with a microdystrophin (called GNT0004), a new gene therapy in boys with Duchenne disease who can still walk. Th… Recruiting

2023-505187-11-00 Duchenne Muscular Dystrophy 2021-03-01
Safety and Efficacy of Induced Pluripotent Stem Cell-derived Engineered Human Myocardium as Biological Ventricular Assist Tissue in Terminal… Recruiting

2024-515708-38-01 Heart failure 2021-01-29
Phase 1b/2 trial of 5-fluorouracil, leucovorin, irinotecan in combination with temozolomide (FLIRT) and bevacizumab for the first-line treat… Recruiting

2024-515580-64-00 metastatic colorectal cancer 2020-12-31
Cultured Autologous Oral Mucosa Epithelial sheet for the Treatment of Bilateral Limbal Stem Cell Deficiency FEMJA for « Feuillet Epithélial … Recruiting

2024-513939-24-00 Bilateral Limbal Stem Cell Deficiency 2020-11-13