Phase I – Other

1,064 trials 249 recruiting

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A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors (ARC-20) Recruiting

2024-519142-70-00 Solid Tumors 2025-11-19
A phase Ib, open-label, ascending dose study to assess safety, tolerability and pharmacokinetics of PIT565 in participants with rheumatoid a… Recruiting

2024-520196-27-00 Rheumatoid Arthritis 2025-10-01
Sotorasib combined with first-line chemotherapy for advanced pancreatic adenocarcinoma Recruiting

2024-516233-12-00 Advanced pancreatic adenocarcinoma 2025-08-08
A Phase 1b, Open-Label Study of CLN-978 for the Treatment of Active, Moderate to Severe Sjogren’s Disease Recruiting

2025-521462-96-00 Sjogren's Disease 2025-08-05
A phase 1 trial to evaluate the safety, tolerability, pharmacodynamics, pharmacokinetics, and immunogenicity of VIS171 in participants with … Recruiting

2024-518976-30-00 Systemic lupus erythematosus 2025-07-02
A Study to Find Out How Nusinersen is Processed in the Body When Given Through the ThecaFlex DRx™ System in Adult and Pediatric Participants… Recruiting

2024-514239-21-00 Spinal Muscular Atrophy 2025-05-21
A Phase I, Open-Label Study of CLN-978 in Patients with Treatment-Refractory Rheumatoid Arthritis (RA) Recruiting

2024-519114-31-00 Treatment-Refractory Rheumatoid Arthritis 2025-05-15
International open-label phase I dose escalation study of dinutuximab beta in combination with vincristine/doxorubicin/cyclophosphamide and … Recruiting

2024-515245-42-00 Ewing Sarcoma 2025-04-24
An Open-Label, Phase 1 Study of the CTPS1 Inhibitor STP938 in Adult Subjects with Advanced Solid Tumors, with a Safety Expansion in Advance… Recruiting

2024-512375-12-00 Solid tumors and ovarian cancer 2025-04-18
Phase IB open label, long-term, extension basket trial of RAY121 to inhibit classical complement pathway in immunological diseases (RAINBOW-… Recruiting

2024-511346-39-00 Immune-mediated necrotizing myopathy 2025-03-28
Dose dense re-challenge of high dose methotrexate (hd-mtx) with glucarpidase (cpg2) for relapsed primary cns lymphoma (pcnsl): A phase 1 tri… Recruiting

2024-511900-17-00 Oncology: RELAPSED PRIMARY CNS LYMPHOMA 2025-02-14
A Study to Investigate the Safety and Efficacy of KQB198 as Monotherapy and in Combination in Participants with Advanced Hematologic Maligna… Recruiting

2024-511457-22-00 Advanced Hematologic Malignancies 2025-01-30
ISA-PET Recruiting

2024-515704-39-00 Invasive Aspergillosis 2025-01-15
A Phase Ib Safety, Pharmacokinetics and Pharmacodynamics Study of TU7710 in Patients with Haemophilia A or B Recruiting

2024-511814-20-00 Hemophilia 2024-12-10
A Study Assessing Adverse Event and How Oral ABBV-453 Moves Through the Body in Adult Participants with Relapsed or Refractory (R/R) Chronic… Recruiting

2023-507637-19-00 Small Lymphocytic Lymphoma 2024-10-15
A Trial Investigating Lu AG22515 in Adult Participants With Moderate-to-Severe Thyroid Eye Disease Recruiting

2023-508693-29-00 Active, moderate-to-severe TED 2024-09-19
A Phase 1 Open-Label Study to Evaluate the Efficacy and Safety of ABBV-400 in Select Advanced Solid Tumor Indications Recruiting

2023-506227-29-00 locally advanced or metastatic solid tumors 2024-08-30
A study to characterize the safety, efficacy, pharmacokinetics of subcutaneous administration of Etentamig (ABBV-383) in patients with relap… Recruiting

2023-507901-32-00 Relapsed or Refractory Multiple Myeloma (R/R MM) 2024-06-28
A Phase 1b/2 Study of JNJ-90014496 in Adult Participants with B-cell Non-Hodgkin Lymphoma Recruiting

2023-506267-33-00 Non-Hodgkin Lymphoid Malignancies 2024-05-29
A Phase 1 Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of Denikitug (GS-1811), an Afucosylated Anti-CCR8 Monoclonal … Recruiting

2022-501684-40-00 Head and Neck Squamous Cell Carcinoma, Non-Small-Cell L 2023-10-05
Phase Ib study of the combination of regorafenib with conventional chemotherapy for the treatment of newly diagnosed patients with multimeta… Recruiting

2023-503322-39-00 Newly diagnosed patients with metastatic (other than lu 2023-06-16
A Study to Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of Furmonertinib in Patients with Non-Small Cell Lung Cancer with A… Recruiting

2023-508349-42-00 Non-Small Cell Lung Cancer (NSCLC) harboring activating 2022-10-18
Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab and a Combined Regimen of Mosunetuzumab and Venetoclax in Patie… Recruiting

2022-501876-24-00 Relapsed or Refractory (R/R) Chronic Lymphocytic Leukem 2022-06-17
Phase I/II clinical trial of autologous hematopoietic stem cell gene therapy in rag1-deficient severe combined immunodeficiency Recruiting

2023-510204-50-00 Severe combined immunodeficiency based on genetic defec 2021-07-23