Therapeutic Exploratory (Phase II)

3,454 trials 1,368 recruiting

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TAR-0520 Gel in taxanes-induced peripheral neuropathy Recruiting

2025-521674-33-00 Taxanes-induced peripheral neuropathy 2025-11-05
A Study to Assess the Efficacy, Safety, and what the body does to RO7837195 in Participants with Moderately to Severely Active Ulcerative Co… Recruiting

2025-520690-39-00 Moderately to Severely Active Ulcerative Colitis (UC) 2025-11-04
Sotagliflozin for the treatment of post-bariatric hypoglycaemia: The ONSIDE study Recruiting

2023-509118-12-00 Postbariatric hypoglycaemia 2025-11-03
A phase 2 placebo-controlled trial to investigate visugromab and nivolumab with or without docetaxel in second-line treatment of participant… Recruiting

2024-516794-70-00 Metastatic non-squamous non-small cell lung cancer 2025-11-03
Study of encorafenib plus cetuximab as rechallenge treatment of BRAF V600E-mutant metastatic colorectal cancer patients: the RefIsh trial Recruiting

2023-509564-22-00 Patients with BRAF V600E-mutant metastatic colorectal c 2025-10-30
Clinical trial evaluating the activity of zanidatamab for the treatment of patients with solid tumors with an alteration of the HER2 gene Recruiting

2025-522169-31-00 Adult Patients with HER2-IHC3+ selected solid cancers ( 2025-10-30
Soothing Pain After ChEmotherapy: Psilocybin As INtervention (SPACE-PAIN) — a randomized controlled pilot trial Recruiting

2024-516936-93-02 chemotherapy-induced peripheral neuropathy, chronic neu 2025-10-28
Platform study to evaluate the efficacy and safety of investigational compound(s) in patients with moderate to severe atopic dermatitis Recruiting

2024-519081-49-00 Moderate to severe atopic dermatitis 2025-10-28
A study to investigate the efficacy and safety of SAR444336 in adults with microscopic colitis in clinical remission. Recruiting

2024-519495-83-00 Digestive system diseases 2025-10-28
Clinical performance study of a new diagnostic test for drug sensitivity evaluation in metastatic colorectal cancer Recruiting

2024-519600-27-00 metastatic colorectal cancer 2025-10-28
– IKF/AIO-QUINTIS – A Randomized Phase II Trial Evaluating Fruquintinib in Combination with Tislelizumab in Microsatellite Stable / Profici… Recruiting

2024-519929-38-00 Metastatic Colorectal Cancer without liver metastases 2025-10-27
An explorative clinical study to assess the potential of intravenously administered sodium thiosulfate in subjects with primary Raynaud’s ph… Recruiting

2023-509432-25-00 Raynaud’s phenomenon 2025-10-24
A Phase 2 Study of the Effects and Safety of PF-07328948 in Adults with Heart Failure (BRANCH-HF) Recruiting

2024-518438-94-00 Heart failure 2025-10-24
Testing ivonescimab in combination with standard chemotherapy in advanced or metastatic gastric and gastroesophageal adenocarcinoma patients Recruiting

2025-520694-39-00 Metastatic or locally advanced irresectable (stage IV) 2025-10-24
FORTIFY – Focused Orticumab Research for Treating inflammation in Coronary Arteries Recruiting

2025-520464-17-00 Atherosclerotic Cardiovascular disease 2025-10-21
A study to evaluate dosing schedules of mirvetuximab soravtansine in patients with epithelial ovarian, primary peritoneal, or fallopian tube… Recruiting

2024-517184-23-00 platinum-resistant advanced high-grade epithelial ovari 2025-10-16
A two-center, randomized, double-blind, placebo-controlled study of intravenous plasma-purified alpha-1 antitrypsin for hospitalized patient… Recruiting

2024-517613-33-00 Chronic Obstructive Pulmonary Disease 2025-10-16
Combination approach with ritlecitinib and nbUVB compared to ritlecitinib alone for treating vitiligo Recruiting

2025-521504-22-00 Vitiligo 2025-10-16
Pharmacokinetics, safety, and tolerability of crinecerfont in subjects with congenital adrenal hyperplasia who are less than 2 years old Recruiting

2024-514127-42-00 Congenital adrenal hyperplasia (CAH) 2025-10-16
A clinical study of patritumab deruxtecan in people with breast cancer Recruiting

2024-514376-40-00 High Risk Early-Stage Triple Negative Breast Cancer (TN 2025-10-15
Hepatic radiotherapy added to standard of care for the treatment of HLA A*02:01 positive Metastatic Uveal Melanoma patients Recruiting

2024-519760-40-00 metastatic uveal melanoma HLA A*02:01 positive 2025-10-14
Clinical trial comparing induction treatment with EGFR-ADC MRG003 alone or in combination with the anti PD1 Pucotenlimab, followed by radioc… Recruiting

2023-510558-18-00 locally advanced head and neck squamous cell carcinoma 2025-10-13
A Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature Recruiting

2024-520137-74-00 Idiopathic Short Stature (ISS) 2025-10-10
The effect of amantadine as add-on therapy for motor fluctuations in advanced Parkinson’s disease: a randomized double-blinded placebo-contr… Recruiting

2023-509728-16-00 advanced Parkinson’s disease 2025-10-10