Therapeutic Exploratory (Phase II)

3,454 trials 1,368 recruiting

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Long-term safety and efficacy evaluation of subcutaneous amlitelimab in adult participants with moderate to severe asthma who completed trea… Ended

2023-503385-24-00 Asthma 2024-03-12
A study of continued treatment with regorafenib in participants with solid tumors who have participated in other Bayer studies Ended

2023-507084-19-00 Solid malignant tumors 2024-03-07
Meningococcal B vaccine in patients with asplenia Ended

2023-508192-36-00 Splenectomy 2024-03-05
Locally Advanced or Metastatic Hepatocellular Carcinoma (HCC): Evaluation of the Optimized Dose, Safety, and Efficacy of Livmoniplimab in Co… Ended

2022-502948-13-00 Hepatocellular Carcinoma 2024-03-01
Study of Acalabrutinib Plus Venetoclax and Rituximab in Participants with Treatment Naïve Mantle Cell Lymphoma Ended

2023-505205-16-00 Treatment Naïve Mantle Cell Lymphoma 2024-02-21
Patient Preference for Route of Administration with Intravenous Infusion Switch to Subcutaneous I-O Regimens in Melanoma Ended

2023-504515-33-00 Melanoma 2024-02-19
Patient Preference Study of SC Pembrolizumab versus IV Pembrolizumab with hyaluronidase (MK-3475A) in multiple cancer types Ended

2023-506017-22-00 Melanoma, Renal Cell Carcinoma, Non-small cell lung can 2024-02-16
ARGX-117 in Deceased Donor Kidney Transplant Recipients at Risk for Delayed Graft Function (Varvara) Ended

2022-503091-89-00 Delayed graft function 2024-02-15
An international prospective open-label, multi-center, randomized, non-comparative phase II study of lutetium [177Lu] vipivotide tetraxetan … Ended

2022-503040-41-00 PSMA PET scan positive Castration-Resistant Prostate Ca 2024-02-09
NeoAdjuvant Dynamic marker - Adjusted Personalized Therapy comparing trastuzumab-deruxtecan versus pacli-/docetaxel+carboplatin+trastuzumab+… Ended

2024-514458-61-01 HER2+ early breast cancer 2024-02-05
ELACESTRANT in Women and Men with CDK4/6 Inhibitor-Naive Estrogen Receptor Positive, HER-2 Negative Metastatic Breast Cancer: An Open-Label … Ended

2023-503214-68-00 metastatic breast cancer 2024-01-31
Study to evaluate the efficacy and safety of BGB-11417 in participants with Waldenström’s Macroglobulinemia Ended

2023-503235-18-00 previously untreated WM 2024-01-31
[68Ga]Ga-FAPI total body PET/CT for improving diagnostic sensitivity and preoperative staging in gastroesophageal cancer and pancreatic canc… Ended

2023-503632-41-01 Pancreatic cancer and gastroesophageal cancer (esophagu 2024-01-30
Pembro-CORE pilot Ended

2022-501306-35-00 First relapse or primary refractory of classical Hodgki 2024-01-26
Phase 2 Platform Study of Novel Immunotherapy Combinations as First-Line Treatment in Participants with PD-L1 Positive Recurrent/Metastatic … Ended

2023-503428-24-00 Neoplasms, Head and Neck 2024-01-19
A bicentric, randomized, double blind, placebo-controlled pilot study to evaluate the efficacy and safety of satralizumab in FSHD1 Ended

2023-504507-81-00 Type 1 facioscapulohumeral muscular dystrophy 2024-01-15
FILOAML-RR-01-OGILAR: Open-label, phase 2 study investigating the efficacy and safety of the addition of oral-azacitidine to salvage treatme… Ended

2022-501372-25-00 Patients aged 18 years and older with relapsed or refra 2024-01-10
ETOP 14-18 CHESS: Immunotherapy, chemotherapy and radiotherapy, followed by surgery or radiotherapy, for patients with newly diagnosed non-s… Ended

2024-511134-12-00 NSCLC, synchronous oligo-metastatic 2023-12-20
Prospective study to evaluate the efficacy of letermovir prophylaxis for the prevention of CMV infection in lung transplant recipients compa… Ended

2023-504384-16-00 lung transplant patients (D+/R-) 2023-12-18
Immune response to the recombinant Zoster Vaccine in people living with HIV over 50 years of age compared to non-HIV age- and gender-matched… Ended

2023-504482-23-00 Human Immunodeficiency Virus (HIV) 2023-12-14
A Phase 2, open-label, multi-centre, multi-national interventional trial to evaluate the efficacy and safety of erdafitinib (ERDA) monothera… Ended

2024-512573-27-01 Muscle-invasive bladder cancer (MIBC) 2023-12-11
Double-blind, randomised, prospective, placebo controlled parallel group phase II study to investigate the effect of glycerol phenylbutyrate… Ended

2024-516897-31-00 Corticobasal Syndrome (CBS) 2023-12-01
Subcutaneous immunoglobulin (HyQvia) against early infections in multiple myeloma: SHIELD Ended

2023-505053-40-00 Multiple Myeloma 2023-11-30
Diagnostic Accuracy Study for OWL-EVO1 as a Lung Cancer EVOC® Probe Ended

2023-503574-20-00 Lung Cancer 2023-11-29