AstraZeneca AB — Sponsor Intelligence | 274 EU Trials

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274 Registered trials

84 Recruiting

175 Completed trials

25 Countries active

204 Unique IMPs

100% Results reported

Phase III

Phase II

Phase I (Other)

Phase III: 129 Phase II/III: 2 Phase II: 56 Phase I/II: 13 Phase III/IV: 2 Phase IV: 3 Phase I: 12 Phase I (Other): 40 Phase I (FiH): 16 Other: 1

Oversight events:

10 serious breaches 32 temporary halts 5 urgent safety measures 1 unexpected event 6 corrective measures across 24 trials

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100%

175 of 175 completed trials have published summary results (EU CTR Article 37 — 12-month obligation).

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Top indications

Non-small cell lung cancer 13 Chronic obstructive pulmonary disease 11 Asthma 11 Chronic kidney disease 6 Systemic lupus erythematosus 5 Triple negative breast cancer 5 Non-small cell lung cancer metastatic 4 Hepatocellular carcinoma 4 Breast cancer 4 Ovarian cancer 4 Non-small cell lung cancer stage III 3 Prostate cancer metastatic 3

Top IMPs

DURVALUMAB 45 RILVEGOSTOMIG 20 TRASTUZUMAB DERUXTECAN 18 DATOPOTAMAB DERUXTECAN 17 OSIMERTINIB 16 INFLIXIMAB 15 MYCOPHENOLATE MOFETIL 15 VOLRUSTOMIG 12 OLAPARIB 11 TREMELIMUMAB 11 CAMIZESTRANT 8 CAPIVASERTIB 8

All trials — page 10

274 total

Phase 2a Study to Assess the Efficacy and Safety of AZD4604 in Adult Patients with Moderate-to-Severe Asthma Uncontrolled on Medium-High Dos… Ended

2023-506000-50-00 Phase II 7 countries (2R)-N-[3-(5-FLUORO-2-{[2-FLUORO-3-(METHYLSULFONYL)PHENYL]AMINO}-4-PYRIMIDINYL)-…
A trial to learn how AZD4604 acts in the body and how safe it is in adults with asthma Ended

2023-510291-32-00 Phase II 3 countries (2R)-N-[3-(5-FLUORO-2-{[2-FLUORO-3-(METHYLSULFONYL)PHENYL]AMINO}-4-PYRIMIDINYL)-…
PET study of changes in [11C]AZ14132516 uptake following administration of multiple AZD7798 doses to patients with Crohn’s disease. Ended

2024-512992-11-00 Phase I (Other) 1 country
A trial to learn how well balcinrenone in combination with dapagliflozin works and how safe it is compared to dapagliflozin alone in adults … Ended

2023-509709-63-00 Phase II 5 countries BALCINRENONE, DAPAGLIFLOZIN; DAPAGLIFLOZIN
A study to investigate the effect of oral ticagrelor on the pharmacokinetics of oral rosuvastatin when given in healthy participants Ended

2024-512197-99-00 Phase I (Other) 1 country
A Phase IIb Two-Cohort, Randomised, Placebo controlled, Double blind, Multi-centre, Dose-ranging Study of AZD5462 in Stable Patients with Ch… Ended

2023-510148-19-00 Phase II 7 countries AZD5462
An Open-label, Single-group, Three-period, Fixed-sequence, Phase I Study to Assess the Pharmacokinetics of AZD6793 Tablets When Administered… Ended

2023-509002-30-00 Phase I (Other) 1 country
A study to investigate the effect on lung function of an approved COPD treatment (BGF, with HFA propellant) compared to BGF formulated with… Ended

2023-506565-57-00 Phase III 3 countries BUDESONIDE, GLYCOPYRRONIUM BROMIDE, FORMOTEROL FUMARATE DIHYDRATE
A clinical research study to learn if baxdrostat works at reducing ambulatory blood pressure and is safe for people with high blood pressure… Ended

2023-507640-36-00 Phase III 9 countries BAXDROSTAT
A Phase I, Randomized, Partial Double-blind, Single dose, 3-Way Cross-over Study to Assess the Lung Exposure Bioequivalence of Budesonide, G… Ended

2023-509914-12-00 1 country
A Phase IIb Study to Evaluate the Safety of Zibotentan/Dapagliflozin in Participants with Cirrhosis-ZEAL-UNLOCK Ended

2023-506893-11-00 Phase II 6 countries ZIBOTENTAN
A placebo-controlled safety and tolerability study of intravenous (IV) and subcutaneous (SC) AZD1163 in healthy volunteers Ended

2023-509574-34-00 Phase I 1 country
A trial to learn how much [11C]savolitinib enters the brains of healthy participants Ended

2023-508334-34-00 Phase I (Other) 1 country
A Study to Investigate Relative Bioavailability of Two Different Dosage Forms for Tozorakimab via Subcutaneous Administration in Healthy Vol… Ended

2023-508041-40-00 Phase I (Other) 1 country
A trial to learn how much budesonide, glycopyrronium, and formoterol fumarate (BGF) gets into and moves throughout the body when it is taken… Ended

2023-504089-43-00 Phase I (Other) 1 country
A study to learn if baxdrostat works at reducing blood pressure and is safe in people with high blood pressure Ended

2023-505499-32-00 Phase III 14 countries BAXDROSTAT
"Efficacy and Safety of Tozorakimab in Symptomatic Chronic Obstructive Pulmonary Disease (COPD) with a History of Exacerbations (MIRANDA)" Ended

2023-505543-39-00 Phase III 12 countries TOZORAKIMAB
A study to investigate the effect of different doses of AZD0780 on low-density lipoprotein cholesterol (LDL-C) levels compared with placebo … Ended

2023-506197-12-00 Phase II 5 countries 1-[6-[[(1S,3S)-3-[[5-(DIFLUOROMETHOXY)PYRIMIDIN-2-YL]AMINO]CYCLOPENTYL]AMINO]PYR…
A trial to learn how baxdrostat affects the heartbeat in healthy participants Ended

2023-506108-23-00 Phase I (Other) 1 country
A Study to Evaluate the Effect of BGF MDI, BFF MDI and Placebo MDI on Exercise Parameters in Participants with COPD Ended

2022-502274-16-00 Phase III/IV 2 countries BUDESONIDE, GLYCOPYRRONIUM BROMIDE, FORMOTEROL FUMARATE DIHYDRATE; FORMOTEROL FU…
PET study of changes in [11C]AZ14132516 uptake following administration of AZD7798 to healthy participants and patients with Crohn’s disease Ended

2023-505471-78-00 Phase I (Other) 1 country
A Phase IIb Randomised, Double-blind, Placebo-controlled, Multi-centre, Dose-ranging Study of AZD3427 in Participants with Heart Failure and… Ended

2022-502382-25-00 Phase II 9 countries AZD3427
Study Understanding Pre-Exposure pRophylaxis of NOVel Antibodies (SUPERNOVA) Ended

2024-512554-15-00 Phase III 6 countries CILGAVIMAB; SIPAVIBART
A Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety and Tolerability of Camizestrant in Post-menopausal … Ended

2022-502277-41-00 Phase I (Other) 2 countries

Showing 217–240 of 274 trials

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