Cardiovascular Diseases

818 trials 341 recruiting

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Pulmonary REsistance modification under treatment with Sacubitil/valsartaN in paTients with HeartFailure with reduced ejection fraction Ended

2024-517975-19-00 Heart Failure with reduced ejection fraction. 6 2022-12-12
A study to learn how well the study treatment asundexian works and how safe it is compared to apixaban to prevent stroke or systemic embolis… Ended

2023-503794-38-00 Prevention of stroke or systemic embolism in atrial fib 5 2022-11-24
A first-in-human study to learn how safe the study treatment BAY3018250 is, how it affects the body, how it moves into, through, and out of … Ended

2022-500505-41-00 Acute ischemic stroke 1 2022-11-08
Impact of dapagliflozin on vascular function in chronic kidney disease patients - (DAPA-VASC) Ended

2024-514887-14-00 chronic kidney disease patients 5 2022-10-18
A multicenter, randomized, open-label, blinded endpoint evaluation, phase 3 study comparing the effect of abelacimab relative to dalteparin … Ended

2024-513992-42-00 venous thromboembolism (VTE) in patients with gastroint 10 2022-09-13
A multicenter trial assessing the impact of lipoprotein(a) lowering with pelacarsen (TQJ230) on the rate of weekly lipoprotein apheresis ses… Ended

2023-508324-35-00 Apheresis 5 2022-08-19
Evaluation of the efficacy of intra venous dornase alfa (Pulmozyme®) on arterial recanalization in post-thrombectomy angiography in patients… Ended

2024-515831-31-00 Ischemic stroke 4 2022-08-19
A multicenter, randomized, open-label, blinded endpoint evaluation, phase 3 study comparing the effect of abelacimab relative to apixaban on… Ended

2023-509569-19-00 venous thromboembolism (VTE) 10 2022-08-10
A study to test whether BI 685509 alone or in combination with empagliflozin helps people with liver cirrhosis caused by viral hepatitis or … Ended

2023-504257-12-00 Portal hypertension 4 2022-07-28
Efficacy and safety of riociguat (MK-4836) in incipient pulmonary vascular disease as an indicator for early pulmonary arterial hypertension… Ended

2023-509695-42-00 Pulmonary vascular disease 4 2022-07-25
Inhaled Imatinib Pulmonary Arterial Hypertension Clinical Trial (IMPAHCT) or A Phase 2b/3, Randomized, Controlled, 24-week Dose Ranging and … Ended

2023-508734-34-00 Pulmonary Arterial Hypertension (PAH) 10 2022-06-30
Phase 2 Study to Assess Efficacy and Safety of CDR132L in Patients with Reduced Left Ventricular Ejection Fraction (≤45%) After Myocardial I… Ended

2023-507569-24-00 Myocardial Infarction, Acute Heart Failure, Left Sided 4 2022-06-20
A Phase 3 Study of Sotatercept in Newly Diagnosed Intermediate- and High-risk Pulmonary Arterial Hypertension (PAH) Patients. Ended

2023-509139-16-00 Therapeutic confirmatory (phase III) 5 2022-05-13
ATILA Project: Aspirin Versus Tirofiban in Endovascular Treatment for Patients With Acute Ischemic Stroke Due to Tandem Lesion Ended

2023-508454-26-00 Acute Ischemic Stroke 6 2022-05-01
A Phase 2 Study of Sotatercept for Combined Postcapillary and Precapillary Pulmonary Hypertension Treatment Ended

2023-509141-12-00 Combined Postcapillary and Precapillary Pulmonary Hyper 4 2022-04-28
A Phase 3, randomized, double-blind, placebo-controlled, multicenter study of IV FDY-5301 in patients with a myocardial infarction (STEMI) Ended

2024-514372-40-00 Anterior ST-Elevation Myocardial Infarction 5 2022-04-12
Study to understand if inclisiran is better than a placebo at lowering LDL-cholesterol,is safe and can have an impact on patient quality of … Ended

2024-511263-28-00 Hypercholesterolemia 6 2022-04-08
A study to evaluate Sotatercept in Participants with PAH WHO FC III or FC IV at High Risk of Mortality Ended

2023-509140-10-00 Pulmonary Arterial Hypertension (PAH) 5 2022-04-05
LOW-DOSE DOBUTAMINE INFUSION AND SINGLE-DOSE TOCILIZUMAB IN ACUTE MYOCARDIAL INFARCTION PATIENTS WITH HIGH RISK OF CARDIOGENIC SHOCK DEVELOP… Ended

2024-515999-13-00 Acute Myocardial Infarction with increased risk of Card 6 2022-03-13
Type of Access to the Blood Circulation During Cardiac Arrest Outside the Hospital Ended

2022-500744-38-00 Out-of-hospital cardiac arrest (OHCA) 4 2022-03-01
Effect of antifibrotic therapy on regression of myocardial fibrosis after transcatheter aortic valve implantation (TAVI) in aortic stenosis … Ended

2024-510869-42-00 aortic stenosis patients with high fibrotic burden 4 2022-02-28
Evaluation of safety i efficacy de-escalation antiplatelet strategies in acute coronary syndrome. Ended

2024-518090-34-00 Acute Coronary Syndrom (ACS) 5 2022-02-07
Escalated single Platelet Inhibition for one month plus Direct oral anticoagulation in patients with Atrial fibrillation and acUte coRonary … Ended

2024-512727-36-00 Patients with atrial fibrillation and ST-segment elevat 6 2021-12-21
Ticagrelor monotherapy after coronary stenting in patients with acute myocardial infarction - A prospective single-centre, single-arm phase … Ended

2024-514224-17-00 Myocardial infarction 4 2021-12-03