Cardiovascular Diseases

818 trials 341 recruiting

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A Study to Investigate the Safety and Efficacy of KER-012 in Combination With Background Therapy in Adult Participants With Pulmonary Arteri… Ended

2022-502378-17-00 Pulmonary Arterial Hypertension 4 2024-03-20
A proof of concept and dose-finding study of XXB750 in patients with heart failure Ended

2023-504678-39-00 Heart Failure 4 2024-03-13
A randomized double-blind placebo-controlled phase 1 study on the safety, tolerability and pharmacokinetics/-dynamics of escalating single i… Ended

2023-507035-37-00 Circulatory shock 1 2024-03-11
A study to learn if baxdrostat works at reducing blood pressure and is safe in people with high blood pressure Ended

2023-505499-32-00 Uncontrolled hypertension (uTHN) defined as blood press 5 2024-03-08
Acetated Ringer´s solution in experimental hypovolemia Ended

2023-503946-30-00 Hypovolemia 6 2024-03-02
PRAISE-MR trial Ended

2023-506634-70-00 Heart failure with preserved ejection fraction Secunda 6 2024-02-29
A single-dose, randomized, two-period, two-sequence, crossover pilot bioequivalence study on formulations containing rivaroxaban and acetyls… Ended

2023-509841-12-00 increased blood clotting 2 2024-02-28
A study to learn how well the study treatment finerenone works and how safe it is in people with long-term decrease in the kidneys’ ability … Ended

2022-503024-27-00 Chronic kidney disease associated with type 1 diabetes 5 2024-02-27
A24110He in a placebo-controlled trial evaluating safety in subjects with elevated plasma triglycerides Ended

2023-509091-42-00 Moderate to severe hypertriglyceridemia 4 2024-02-27
Stopstudy Ended

2023-505143-39-00 Transgender women using long-term gender-affirming horm 6 2024-02-23
A randomized, placebo-controlled, parallel-group, investigator- and participant-blinded Phase 2a study to investigate the efficacy, safety, … Ended

2023-506741-34-00 Atherosclerotic cardiovascular disease 4 2024-02-16
A study to test whether BI 685509 helps people with liver cirrhosis and high blood pressure in the portal vein (main vessel going to the liv… Ended

2023-506083-13-00 clinically significant portal hypertension (CSPH) in de 4 2024-02-16
A study to investigate the effect of different doses of AZD0780 on low-density lipoprotein cholesterol (LDL-C) levels compared with placebo … Ended

2023-506197-12-00 Dyslipidemia Dyslipidemias are alterations to the plasm 4 2024-02-07
EMPagliflozin after Aortic Valve Replacement - the EMPAVR study Ended

2023-504731-40-01 Aortic stenosis 6 2024-02-07
A trial to learn how baxdrostat affects the heartbeat in healthy participants Ended

2023-506108-23-00 Treatment-resistant hypertension 3 2024-02-06
MK-0616-013 Ended

2022-502777-42-01 Hypercholesterolemia 5 2024-01-16
Individualized anti-platelet therapy in patients with stable coronary artery disease undergoing stenting Ended

2023-504078-39-01 Stable coronary artery disease 6 2024-01-11
A study to learn more about how well BAY 3018250 works and how safe it is for people with proximal deep vein thrombosis Ended

2023-503315-15-00 Thrombolysis of symptomatic proximal vein thrombosis 4 2023-12-20
A Study to Learn How Different Amounts of the Study Medicine Called PF-07293893 are Tolerated and Act in the Body of Healthy Adults. Ended

2023-508171-36-00 heart failure with preserved ejection fraction 3 2023-12-15
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Oral Inhalation of Seralutinib for the … Ended

2023-503614-80-00 Pulmonary Arterial Hypertension 5 2023-12-14
A first-in-human, randomized, participant and investigator blinded, placebo-controlled single and multiple ascending dose study to assess th… Ended

2023-505542-26-00 Heart failure (HF) 1 2023-11-30
A study to test whether BI 765845 helps people who have had a heart attack Ended

2022-502788-39-00 acute myocardial infarction 4 2023-11-27
A large global trial to evaluate the efficacy and safety of milvexian in reducing recurrent cardiovascular events in patients after a heart … Ended

2022-501418-69-00 Acute Coronary Syndrome 5 2023-11-21
MK-1403 Single Dose Formulation PK Study Ended

2023-507984-20-00 Atherosclerosis 3 2023-11-17