Cardiovascular Diseases

818 trials 341 recruiting

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Rivaroxaban sotorasib interaction study Ended

2023-505557-41-00 Healthy subjects 6 2023-11-09
Routine versus selective protamine administration to reduce bleeding complications after transcatheter aortic valve implantation Ended

2023-504205-36-00 Aortic stenosis 11 2023-11-01
OPEN LABEL, FOUR-PERIOD, TWO-SEQUENCE, FULLY-REPLICATED, RANDOMIZED, SINGLE DOSE COMPARATIVE STUDY TO ASSESS BIOEQUIVALENCE OF Polypill AAR … Ended

2023-505572-30-00 Study performed on healthy volunteers 2 2023-10-24
A randomized, open-label, single dose, 2-way crossover bioequivalence study comparing ticagrelor 90 mg hard capsules (PG402 [Celon Pharma]) … Ended

2023-504116-14-00 Prevention of atherothrombotic events in adult patients 2 2023-10-17
Randomized, open-label, single dose, three-period, three treatment cross-over bioavailability study comparing test products Rosuvastatin/Eze… Ended

2023-507048-35-00 not applicable (submitted trial is bioavailability stud 3 2023-10-11
A controlled, randomized, first-in-human study of AP31969 investigating single and multiple ascending doses and the effect of food in health… Ended

2023-505424-57-00 Atrial Fibrillation (cardiac arrhythmia) 1 2023-10-04
A clinical study of MK-0616 for people with high amounts of low-density lipoprotein cholesterol Ended

2022-502782-14-00 Heterozygous Familial Hypercholesterolemia (HeFH) 5 2023-09-28
Prospective, monocentric, exploratory phase II study for the evaluation of the diagnostic use of the tracer PET (18F) -Flutemetamol (Vizamyl… Ended

2024-517971-19-01 cardiac amyloidosis 4 2023-09-20
A Translational Phase 1B, 2-Part Study to Evaluate Pharmacokinetics, Safety and Pharmacodynamics of Treatment with ATX-304 Na Salt Tablets. Ended

2023-505967-36-00 Obesity with prediabetes or type 2 diabetes mellitus 3 2023-09-15
A study to learn how safe the study treatment BAY2701250 is, how it affects the body and how it moves into, through and out of the body in h… Ended

2023-503368-18-00 Pulmonary hypertension due to left heart disease 1 2023-09-14
A randomized, open-label, single dose, cross-over bioavailability study evaluating the drug-drug interaction between Tritace 10, 10 mg, tabl… Ended

2023-505887-12-00 NA - study in healthy subjects 3 2023-09-13
The impact of Empagliflozin on Left atrIal Volume and the feasibility of using Fitbit and mHealth to prescribe Exercise in non-diabetic Pre-… Ended

2024-512062-34-00 Pre-Heart Failure (Non-diabetic) 4 2023-08-30
A Phase IIb Randomised, Double-blind, Placebo-controlled, Multi-centre, Dose-ranging Study of AZD3427 in Participants with Heart Failure and… Ended

2022-502382-25-00 Heart Failure and Pulmonary Hypertension due to Left He 4 2023-08-24
A first in human single dose escalation study to investigate the safety, tolerability, pharmacokinetics, and pharmcodynamics of BAY 3389934 … Ended

2022-502866-25-00 Sepsis associated disseminated intravascular coagulatio 1 2023-08-18
Randomized, open-label, single dose, four-period, cross-over drug-drug interaction study comparing reference products Crestor 20 mg film coa… Ended

2023-505153-41-00 Not applicable (submitted trial is a study in healthy s 3 2023-08-17
RANDOMISED, CROSSOVER BIOEQUIVALENCE CLINICAL TRIAL OF APIXABAN 5 MG CAPSULES VS APIXABAN 5 MG FILM-COATED TABLETS, AFTER A SINGLE ORAL DOSE… Ended

2023-506035-15-00 thrombosis 2 2023-08-16
Initiation of angiotensin receptor-neprilysin inhibitor (ARNi) and sodium-glucose cotransporter-2 inhibitors (SGLT2i) in patients with heart… Ended

2022-502409-14-00 Heart failure with reduced ejection fraction 11 2023-08-04
A Study to Learn About the Study Medicine Called PF-07293893 in Healthy Adults, and How Different Doses of Study Medicine are Tolerated and … Ended

2023-504921-37-00 heart failure with preserved ejection fraction (HFpEF) 1 2023-08-04
A trial to learn how well REGN9933 works for preventing blood clots after knee replacement surgery in adult participants Ended

2022-501470-18-00 Thromboembolic disease 4 2023-06-26
Randomized, open-label, single dose, two-period, cross-over bioequivalence study comparing test formulation Rosuvastatin/Amlodipine/Ramipril… Ended

2023-503822-38-00 Not applicable (submitted trial is a bioequivalence stu 2 2023-06-19
A clinical study of MK-1403 in healthy men Ended

2023-504695-23-00 Atherosclerosis 1 2023-06-15
Randomised, crossover bioequivalence clinical trial of apixaban 5 mg film-coated tablets, after a single oral dose administration to healthy… Ended

2023-503557-35-00 thromboembolism 2 2023-06-08
A Study of Olezarsen (ISIS 678354) in Participants With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease, or With Severe Hype… Ended

2022-503022-13-00 Hypertriglyceridemia, Cardiovascular Diseases, Atherosc 5 2023-06-08
Plethysmography with acetylcholin and carbacholin – A clinical method study Ended

2023-503908-87-00 Vascular dysfunction 4 2023-06-02