Eye Diseases

237 trials 74 recruiting

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Trial of Sibeprenlimab in the Treatment of Sjögren’s Disease Ended

2024-516295-14-00 Treatment of Sjögren’s disease 4 2025-09-17
A Safety, and Tolerability Study of VRDN-003 in Participants with Thyroid Eye Disease (TED) Ended

2024-519417-57-00 Thyroid eye disease 5 2025-06-25
An open-label safety and tolerability clinical trial of PST-611 in dry age-related macular degeneration. Ended

2024-519025-37-00 Dry age-related macular degeneration. 1 2025-06-19
LUCIA: A Phase 3 randomized, double-masked study comparing the efficacy of EYP-1901 against aflibercept Ended

2024-518030-83-00 Wet age-related macular degeneration (wAMD) 5 2025-06-05
A Study Investigating the Efficacy and Safety of Intravitreal Injections of ANX007 in Participants with Dry Age-Related Macular Degeneration… Ended

2024-515022-88-00 Dry Age-Related Macular Degeneration (AMD) with geograp 5 2025-03-03
A Phase 3 Study of Brepocitinib in Adults with Active, Non-Infectious, Non-Anterior Uveitis (CLARITY) Ended

2024-515089-15-00 active non-infectious uveitis (intermediate uveitis, po 5 2025-02-28
An Efficacy, Safety, and Tolerability Study of VRDN-003 in Participants with Chronic Thyroid Eye Disease (TED) Ended

2024-514973-23-00 Thyroid eye disease 5 2025-02-25
A study to test whether BI 764524 helps people with an eye condition called diabetic retinopathy Ended

2023-508891-12-00 Diabetic retinopathy 4 2024-11-28
A randomized study to evaluate the Efficacy and Safety of Intravitreal EYE103 Compared to Anti-VEGF (in patients with Diabetic Macular Edema… Ended

2024-510944-30-00 Diabetic Macular Edema 10 2024-11-22
ReNEW: A Phase 3, Randomized, Double-Masked, Placebo-Controlled Clinical Trial to Evaluate the Efficacy, Safety, and Pharmacokinetics of Sub… Ended

2024-511482-11-00 Dry Age-Related Macular Degeneration (Dry AMD) 5 2024-11-20
MAD Ended

2024-516379-34-00 Myopia 6 2024-08-02
Allogeneic Tissue Engineering (Nanostructured Artificial Human Cornea) in Patients With Corneal Trophic Ulcers in Advanced Stages, Refractor… Ended

2024-515481-13-00 Corneal trophic ulcers refractory to conventional treat 7 2024-07-05
Study of Subretinally Injected AAVB-081 in Patients with Usher Syndrome Type IB (USH1B) Retinitis Pigmentosa Ended

2024-518489-29-00 Usher Syndrome Type 1B (USH1B) Retinitis Pigmenotsa 7 2024-07-01
(Treatments to shrink tumors before surgery, radiation or other forms of nondrug therapy) to use the investigational drug (Darovasertib) in … Ended

2023-506683-14-00 Uveal Melanoma 4 2024-06-14
A Randomized, Partially Masked, Controlled, Phase 3 Clinical Study to Evaluate the Efficacy and Safety of RGX-314 Gene Therapy in Participan… Ended

2023-503666-23-00 Neovascular age-related macular degeneration 5 2024-06-07
NAC Attack, A Phase III, Multicenter, Randomized, Parallel, Double Masked, Placebo-Controlled Study Evaluating the Efficacy and Safety of Or… Ended

2022-501438-46-00 Retinitis Pigmentosa 5 2024-01-22
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants with Moderate-to-Severe Thy… Ended

2023-503669-50-00 Moderate-to-Severe Thyroid Eye Disease 5 2023-12-27
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants with Moderate-to-Severe Thy… Ended

2023-503309-13-00 Moderate-to-Severe Thyroid Eye Disease 5 2023-11-29
Safety and Efficacy of multiple doses of the PAINLESS Nerve Growth Factor CHF6467 in paediatric subjects with Optic Pathway Glioma (OPG). A … Ended

2024-515753-16-00 Optic Pathway Glioma (OPG) 9 2023-05-18
TEMP-PREVENT Ended

2024-512133-33-00 Pseudoxanthoma Elasticum 5 2023-04-26
Clinical study to evaluate the safety and tolerability of SPVN06 (novel gene therapy) in a subset of patients with rod cone dystrophy (RCD). Ended

2022-501250-12-01 Inherited retinal dystrophies 7 2023-03-17
Study to evaluate the long-term safety of GT005 in participants having macular degeneration that led to geographic atrophy in their eyes and… Ended

2024-510946-15-00 Geographic atrophy (GA) secondary to age-related macula 9 2022-12-08
A Randomized Intervention, Multi-Center Study to Determine the Role of Dexamethasone eye drops against proliferative retinopathy of prematur… Ended

2023-505318-97-00 Retinopathy of Prematurity 5 2022-09-22
Long Term Follow-Up study of Gene Therapy Trial for Patients with Retinitis Pigmentosa (progressive reduction in vision) due to a gene defec… Ended

2024-511411-25-00 X-Linked Retinitis Pigmentosa caused by mutations in th 5 2022-08-25