Hemic and Lymphatic Diseases

593 trials 238 recruiting

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A Single-Blind randomized trial of High-Dose versus Standard-Dose Inactivated Influenza Vaccine in Adult Patients Treated for an Hematologic… Recruiting

2023-505357-40-00 Hematological cancer 5 2023-09-18
FLUCLORIC - Randomized multicentric Phase III study comparing the efficacy of two reduced intensity conditioning regimens (clofarabine/busul… Recruiting

2022-502019-12-00 acute myeloid leukemia 5 2023-09-14
A multi-center randomized, double blinded phase IIb trial evaluating oral pooled fecal microbiotherapy MaaT033 to prevent allogeneic hematop… Recruiting

2022-501831-18-00 Patients with hematologic malignancies and undergoing a 4 2023-09-13
Age-adjusted high-dose chemotherapy followed by autologous stem cell transplantation or conventional chemotherapy with R-MP as first-line tr… Recruiting

2024-512320-11-00 Primary diffuse large B-cell lymphoma of the central ne 5 2023-08-09
A trial to test if different amounts of KTX-1001 are safe and tolerable in people with the bone marrow cancer multiple myeloma that has come… Recruiting

2022-500801-41-00 Relapsed and Refractory Multiple Myeloma 1 2023-07-26
Efficacy and Safety of BT200 (rondaptivon pegol) in Patients with Type 2B von Willebrand disease Recruiting

2024-518294-34-01 Von Willebrand's Disease Type 2B 4 2023-07-21
First-line combination of Bcl-2 inhibitor and monoclonal antibody followed by administration of Bcl-2 inhibitor alone or combination of Bcl-… Recruiting

2023-510431-11-00 Chronic Lymphocytic Leukemia 4 2023-07-21
A Phase 1/2 Open Label non randomized Study, multicentric, single arm evaluating the Safety and Efficacy of Gene Therapy of the severe comb… Recruiting

2024-513652-15-00 Severe Combined Immuno-Deficiency (SCID) caused by bial 7 2023-07-19
Phase 1 Study of Allo-RevCAR01-T-CD123 in Patients With Selected CD123 Positive Hematologic Malignancies Recruiting

2022-501797-19-00 Acute Myeloid Leukemia (AML) 1 2023-07-13
A multicentre, randomized trial in adults with de novo Philadelphia-Chromosome positive acute lymphoblastic leukemia to assess the efficacy … Recruiting

2024-517966-40-00 Acute lymphoblastic leukemia (ALL), de novo, Ph/BCR::AB 4 2023-07-13
Combination treatment of Belantamab Mafodotin and Venetoclax in treatment of relapsed and refractory t(11;14) Multiple Myeloma (Phase I/IIa)… Recruiting

2024-511794-30-00 Multiple Myeloma 9 2023-06-28
Phase 1/2 multicenter, open-label, dose-escalation study of IDP-121 in patients with relapsed/refractory hematologic malignancies (CASSANDRA… Recruiting

2024-519194-19-00 Chronic lymphocytic leukemia (CLL) 7 2023-06-06
Trial evaluating the safety and efficacy of Venetoclax in addition to a standard conditioning regime in patients with certain forms of leuke… Recruiting

2024-514688-24-00 Patients with myelodysplastic syndrome (MDS), chronic m 9 2023-05-26
A Study in Adult Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) to Evaluate How Safe Long-term Treatment with Pozelimab + Cemdisira… Recruiting

2023-510336-36-00 Paroxysmal nocturnal hemoglobinuria (PNH) 5 2023-05-05
A Randomized, Open-label, Phase 3 Study of Acalabrutinib in Combination with Rituximab and Reduced Dose CHOP (R-miniCHOP) in Older Adults wi… Recruiting

2022-501187-18-00 a. Diffuse large B-cell lymphoma (DLBCL) not otherwise 5 2023-04-24
An open-label, dose-escalation, dose-finding, and proof-of-concept trial of SP-420 in subjects with transfusion-dependent α- or β-thalassemi… Recruiting

2023-507396-21-00 transfusion-dependent α- or β-thalassemia or low-risk m 4 2023-03-16
Monocentric phase 1 dose-escalation study of siltuximab in combination with idarubicin and cytarabine chemotherapy in patients with poor pro… Recruiting

2022-501171-14-00 adult patients with acute myeloblastic leukemia (AML) o 3 2023-03-13
phase I/II b study of atezolizumab and BEGEV as first salvage treatment in patients with relapsed or refractory Hodgkin’s lymphoma candidate… Recruiting

2024-511631-10-00 Hodgkin’s lymphoma 9 2023-02-27
Randomized prospective trial evaluating the efficacy of the antiCD38 monoclonal antibody isatuximab in the treatment of PCRA by major ABO mi… Recruiting

2024-514351-14-00 Pure cell red aplasia by major ABO mismatch after allog 4 2023-02-20
Safety and efficacy of hCD1a-CAR T (OC-1) therapy, in patients with relapsed/refractory (R/R) T-cell acute lymphoblastic leukemia/lymphoma (… Recruiting

2024-514591-40-00 T-cell Acute Lymphoblastic Leukemia 1 2023-01-31
Phase 2 Study of Luspatercept in Adults and Adolescents with Alpha (α)-thalassemia Recruiting

2022-502328-35-00 Alpha (α)-thalassemia 4 2023-01-30
Use of nivolumab (N) followed by chemotherapy: bendamustine, gemcitabine and dexamethasone (BGD) with autologous bone marrow transplantation… Recruiting

2024-515064-31-00 Refractory / relapsed Hodgkin's lymphoma 4 2022-12-01
A Phase 2 Study to Evaluate Safety and Efficacy of Teclistamab-,Talquetamab- and JNJ-79635322-based Combination Regimens in Participants wit… Recruiting

2024-517382-17-00 Newly Diagnosed Multiple Myeloma in patients eligible f 4 2022-11-30
A Phase 2 Study of the Efficacy and Safety of a Dose of Donor-Derived CD19-targeted CAR T cells. Recruiting

2024-516091-15-00 Relapsed Acute Leukemia 4 2022-11-23