Hemic and Lymphatic Diseases

593 trials 238 recruiting

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A phase III, randomised, open-label, Multicenter International Trial comparing ruxolitinib with either HydRoxycarbamIDe or interferon Alpha … Recruiting

2024-516109-21-00 Polycythaemia Vera (PV) 5 2024-12-09
LATE-R trial. A Phase II, Single-Arm, Open-Label, Multicenter Study to Evaluate the Efficacy of Axicabtagene Ciloleucel in Patients with Lat… Recruiting

2024-512835-53-00 Diffuse Large B-Cell Lymphoma 4 2024-11-20
Bomedemstat vs Hydroxyurea for Essential Thrombocythemia Recruiting

2023-505232-36-00 Essential thrombocythemia 5 2024-11-15
Study of posaconazole prophylaxis in patients receiving hematopoietic stem cell allograft (allo-HSC) at high risk of invasive fungal infecti… Recruiting

2024-511507-42-00 30 adult patients due to receive an allograft for a mye 4 2024-11-08
Hyper-CVAD/MA for high-risk aggressive B-cell lymphomas: a single-centre academic phase II trial (HYPERION) Recruiting

2023-505990-34-00 Lymphoma 4 2024-11-08
A Phase II randomized trial of RSV vaccination in allogeneic hematopoietic stem cell transplant recipients (RSV-Allo study) Recruiting

2024-513290-53-00 allogeneic - Hematopoietic Stem Cell Transplantation 10 2024-11-07
CAR123 T cell treatment of relapsed/refractory hematologic malignancies. Recruiting

2022-503165-30-00 Relapsed/refractory CD123+ hematological malignancies: 1 2024-10-23
A multicenter, single-arm phase II study to assess the safety, tolerability, and efficacy of Isatuximab in adult patients with cytologic or … Recruiting

2023-507899-47-00 Cytologic or molecular relapsed/refractory CD38 positiv 4 2024-10-22
VEX-AZA: Treating VEXAS Syndrome with Azacitidine. A Single-Arm, Multicenter Phase II Study on the Efficacy and Safety of Azacitidine in Pat… Recruiting

2024-510715-30-00 VEXAS 4 2024-09-26
JAKAHDI - JAK inhibitors in acquired hemophagocytic syndrome in the ICU Recruiting

2023-504513-77-00 Adult patients older than 18 years. Patients admitted t 4 2024-09-16
Improved Recovery by Iron following Surgery with blood loss, a double-blind multi-centre randomized controlled phase III drug trial (the IRI… Recruiting

2022-502776-22-00 Anemia 5 2024-09-05
Self-administration of subcutaneous Elranatamab in the patients’ homes (ERICA) Recruiting

2023-507876-30-00 Multiple Myeloma 4 2024-09-04
A multicenter, phase 2 randomized, open label study to evaluate the efficacy and security of zanubrutinib in combination with obinutuzumab i… Recruiting

2023-504647-14-00 Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic 4 2024-09-02
PHASE II STUDY OF AZACITIDINE IN COMBINATION WITH LOW DOSE INTENSITY VENETOCLAX IN PATIENTS WITH ACUTE MYELOID LEUKEMIA WITH INTEGRATION OF … Recruiting

2023-510415-19-00 Acute Myeloid Leukemia 4 2024-08-28
HOVON 170 DLBCL: ANTICIPATE: Prevention of ANThracycline-Induced Cardiac dysfunction by dexrazoxane In PATients with diffusE large B-cell ly… Recruiting

2023-505377-32-00 Diffuse large B-cell lymphoma (DLBCL) 5 2024-08-15
A Study of DR-01 in Adult Subjects With Large Granular Lymphocytic Leukemia or Cytotoxic Lymphomas Recruiting

2023-503550-13-00 Large Granular Lymphocytic Leukemia or Cytotoxic Lympho 7 2024-08-08
A study of the safety and efficacy of MB-dNPM-1-TCR.1 in patients with relapsed or refractory AML. Recruiting

2023-505806-41-00 Acute myeloid leukemia 7 2024-08-01
A Global Multicenter, Open Label, Randomized Phase 3 Registrational Study of Lisaftoclax (APG-2575) in Previously Treated Patients with Chro… Recruiting

2023-508005-24-00 Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma 5 2024-08-01
A Long-term Follow-up Study of Subjects With Malignancies Treated With CRISPR CAR Cellular Therapies Recruiting

2024-512479-11-00 Solid Malignancy 9 2024-07-26
Randomized Phase 2 study testing two conditioning regimen with a single prophylaxis of graft-versus-host disease by cyclophosphamide and met… Recruiting

2023-509042-35-01 Adults patients will be included in the hematology depa 4 2024-07-18
A Phase 2 study to evaluate the efficacy and safety of selinexor monotherapy in subjects with JAK inhibitor-naïve myelofibrosis and moderate… Recruiting

2024-511309-47-00 moderate thrombocytopenia 4 2024-07-17
Improvement of MRI assessed cerebral Perfusion and oxygenation by luspatercept-induced Anemia Correction in non-transfusion dependent Thalas… Recruiting

2023-504908-28-01 Non-transfusion dependent beta-thalassmia 11 2024-07-14
Phase I/II, open-label, multi-center study to evaluate the safety and efficacy of glyco-humanized polyclonal antibody directed against tumor… Recruiting

2023-509648-88-00 Peripheral T cells lymphoma (PTCL) 9 2024-07-09
CARMOD - Golcadomide (BMS-986369) post-CAR T-cell in R/R Aggressive large B-cell lymphoma patients with high risk of relapse Recruiting

2023-506705-20-00 relapsed or refractory patients with aggressive large B 4 2024-06-14