Musculoskeletal Diseases

438 trials 179 recruiting

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Study to compare the effectiveness and tolerability of the injectable combination of Diclofenac and Thiocolchicoside against injectable Dicl… Ended

2024-512786-13-00 Acute moderate to severe low back pain 5 2024-12-13
Randomized controlled trial comparing clinical outcomes of Instant MSC Product accompanying Autologous Chondron Transplantation (IMPACT) for… Ended

2024-514612-27-01 Symptomatic articular cartilage lesion of the knee (fem 5 2024-12-01
A first-in-human study to investigate safety and tolerability of SAR446959 in participants with osteoarthritis of the knee Ended

2024-514015-96-00 Osteoarthritis 1 2024-11-20
A Phase 1, multiple-dose, single-center, randomized, open-label, 2-period, 2-treatment crossover systemic bioavailability study of diclofena… Ended

2024-515954-26-00 Phase I Study in healthy male and female volunteers. In 3 2024-11-19
Evaluation of the benefit of subcutaneous injection (Localized Tissue Hydration) of physiological solution in the treatment of chronic low b… Ended

2024-510625-25-00 chronic common low back pain 4 2024-11-14
Melatonin for Chronic back pain Ended

2023-503530-41-00 Chronic back pain 5 2024-11-07
A Single Dose, Fasting state, Crossover Replicate Bioequivalence Study of Naproxen 500 mg/Esomeprazole 20 mg, modified-release tablets (Anti… Ended

2024-515662-14-00 healthy subjects 2 2024-10-31
Ibuprofen 200 mg bioequivalence study Ended

2024-516161-36-00 not applicable (submitted trial is BE) 2 2024-09-13
A Randomized, Single-dose, Crossover, Two-period, Pilot Comparative Bioavailability Study of Alendronate 70 mg effervescent vs. Fosamax 70 m… Ended

2024-513615-26-00 not applicable (submitted trial is a comparative bioava 2 2024-09-12
A Double-Blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of Infigratinib in Children with Achondroplasia Ended

2023-506130-67-00 Achondroplasia 5 2024-08-20
Evaluation of vamorolone CYP3A4 induction on midazolam (a sensitive CYP3A4 substrate) pharmacokinetics Ended

2024-513845-36-00 Phase I study in healthy male volunteers. Intended indi 3 2024-08-13
A Prospective Real-World Evidence Study evaluating the effects of Voltaren use on Mobility and QoL of subjects with knee osteoarthritis (OA)… Ended

2024-510839-22-00 Mild/non-serious osteoarthritis (OA) of the knee. 11 2024-07-18
GO TEST FINALE Ended

2024-511111-13-01 Gout 6 2024-07-09
A placebo-controlled, double-blinded, randomized, dose-finding trial using a combination of apocynin and paeonol (APPA) for the treatment of… Ended

2023-508791-11-00 Knee osteoarthritis 4 2024-07-08
Study to evaluate the pharmacokinetics, safety and tolerability of Secukinumab in patients with GCA or PMR Ended

2023-507667-19-00 Polymyalgia rheumatica (PMR) 3 2024-06-06
A Randomized, Double-blind, Controlled, Parallel-group, Single Dose, Three arm Study to Compare the Pharmacokinetic Similarity of MAB-22 Ver… Ended

2023-509749-11-00 Healthy volunteers 2 2024-06-05
A study to learn how vamorolone affects the body, how safe it is and how it moves into, through and out of the body in healthy male particip… Ended

2024-512101-60-00 Phase I study in healthy male volunteers. Intended indi 3 2024-06-05
LIC-block with Lidocaine or Ropivacaine for closed reduction of wrist fracture Ended

2024-510572-20-00 Distal radius fractures with need of acute closed reduc 6 2024-04-23
Combining short and long-acting local anaesthetics in ultrasound-guided infraclavicular brachial plexus nerve block. Ended

2023-510028-63-00 Patients undergoing hand surgery for antebrachial fract 11 2024-04-18
A study to assess the efficacy and safety of tigulixostat at different doses as compared to a control drug (allopurinol) in gout patients wi… Ended

2022-501421-20-00 Gout with hyperuricemia 5 2024-04-09
A Phase 2, Randomized, Double Blind, Placebo Controlled Study to Evaluate the Efficacy and Safety of Rosnilimab in Subjects with Moderate to… Ended

2023-504564-42-00 Moderate to Severe Rheumatoid Arthritis 4 2024-04-08
A Phase 1/2a Randomized, Double-Blind Placebo-controlled Study of Intra-articular Allocetra in Knee Osteoarthritis Ended

2023-508748-23-00 Knee osteoarthritis 9 2024-03-26
A Study to Learn How Different Amounts of the Study Medicine Called PF-07328948 are Tolerated and Act in the Body in Healthy Adults Ended

2023-509054-54-00 Heart failure 3 2024-03-19
A trial of prednisolone in combination with SPI-62 in participants with polymyalgia rheumatica (PMR) Ended

2023-507721-41-00 polymyalgia rheumatica 3 2024-03-11