Musculoskeletal Diseases

438 trials 179 recruiting

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A first-in-human proof-of-concept study with NVDX3, an osteogenic implant of human allogenic origin, in the treatment of distal radius fract… Ended

2023-508321-27-00 Distal radius fractures 7 2023-08-08
Single Dose Crossover Comparative Bioavailability and Food Effect Study of Celecoxib 10 mg/1 mL Oral Suspension versus Celebrex®️ (celecoxib… Ended

2023-504052-99-00 Musculoskeletal and connective tissue disorders, Dysmen 2 2023-07-31
A study to test how kidney problems influence the blood concentrations of efgartigimod Ended

2023-503992-88-00 renal impairment 3 2023-07-14
Safety and efficacy of NMD670 in ambulatory adult patients with Type 3 spinal muscular atrophy (SYNAPSE-SMA) Ended

2024-516321-31-00 Type 3 spinal muscular atrophy 4 2023-07-07
Efficacy and tolerability of horse chestnut seed extract on swelling in patients undergoing meniscus surgery: a placebo-controlled, randomiz… Ended

2022-501154-11-00 post-operative swelling, pain and edema 4 2023-05-31
Study of M5049 in DM and PM Participants (NEPTUNIA) Ended

2022-501351-82-00 Dermatomyositis, Polymyositis 4 2023-05-23
Safety, tolerability and pharmacokinetics of intra‐articular (IA) single ascending dose of 4P‐004 in patient with Kellgren and Lawrence grad… Ended

2022-500271-31-00 Knee osteoarthritis 3 2023-05-10
A Phase 1 Study Evaluating Relative Bioavailability of Sprinkled Ritlecitinib in Applesauce, Yoghurt, and Strawberry Jam and Evaluating the … Ended

2022-502872-22-00 Alopecia Areata, Rheumatoid Arthritis, Vitiligo, Ulcera 3 2023-04-28
A study to test if izokibep improves psoriatic arthritis symptoms and to see how safe izokibep is Ended

2022-501362-22-00 Psoriatic Arthritis 10 2023-04-18
A multicentre, randomised, double-blind, placebo-controlled and open label extension study to assess the efficacy, safety, and pharmacokinet… Ended

2024-512265-13-00 Duchenne Muscular Dystrophy 4 2023-04-13
A 2-stage, Adaptive, Randomised, Double-blind, Placebo-controlled, Multicentre Study to Evaluate Dose and Treatment Effect of Pentosan Polys… Ended

2022-500228-31-01 Knee osteoarthritis pain 10 2023-03-31
Efficacy of a fixed combination of diclofenac 75 mg + thiocolchicoside 4 mg as solution for injection, in relieving back pain symptoms. Cont… Ended

2024-518753-42-00 Low back pain (LBP). LBP is one of the most frequent an 5 2023-03-30
A phase 2b clinical trial to evaluate efficacy and safety of weekly doses of TransCon CNP compared with placebo in participants with achondr… Ended

2024-515469-32-00 Achondroplasia in Children and Adolescents 4 2023-03-02
Thiamine Against Chronic Rheumatoid Arthritis Fatigue Ended

2022-500922-13-00 Rheumatoid Arthritis 10 2023-02-16
A proof-of-concept study to examine QUC398 in participants with knee osteoarthritis Ended

2023-509274-28-00 Knee osteoarthritis 4 2023-02-03
Clinical trial on Spinal Anaesthesia vs. General Anaesthesia (SAGA) on recovery after hip and knee replacements Ended

2022-501221-21-00 Osteoarthritis of the hip and knee 6 2023-02-03
REDUCE PMR: Rituximab Effect on Decreasing glUcoCorticoid Exposition in newly diagnosed PolyMyalgia Rheumatica Ended

2024-513544-28-00 Polymyalgia Rheumatica 6 2023-02-01
Pragmatic, randomized, multicentric, double-blind, controlled clinicial trial on the treatment of acute gout attacks with prednisolone versu… Ended

2024-514738-18-00 gout, acute gout attack 6 2023-01-12
Phase 2 Randomized, Double-blind, Placebo-controlled Study of the Effect of EDG-5506 on Biomarkers in Adults with Neuromuscular Disease Ended

2022-500215-39-00 McArdle Disease 4 2022-12-06
A proof of concept study with NVD-003, an autologous osteogenic bone graft, in the treatment of congenital pseudarthrosis of the tibia in pe… Ended

2024-515478-29-00 Congenital pseudarthrosis of the tibia 9 2022-11-28
A Phase 3 study to determine the Efficacy and Safety of Losmapimod in Treating Patients with Facioscapulohumeral Muscular Dystrophy (REACH) Ended

2024-512737-33-00 Facioscapulohumeral Muscular Dystrophy (FSHD) 5 2022-09-30
A trial of prednisolone in combination with SPI-62 or placebo in participants with polymyalgia rheumatica (PMR) Ended

2024-517406-29-00 Polymyalgia rheumatica (PMR) 4 2022-07-26
Open-label trial to check the safety and tolerability of RTX-GRT7039 injections for pain associated with osteoarthritis of the knee. Ended

2024-515709-24-00 Moderate to severe pain associated with Osteoarthritis 5 2022-07-26
A MULTICENTER, PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF SPIRONOLACTONE FOR THE TREATMENT OF ACTIVE RHEUMATOID ARTH… Ended

2024-516884-10-00 RHEUMATOID ARTHRITIS 5 2022-06-22