Musculoskeletal Diseases

438 trials 179 recruiting

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A Single Dose, Fed state, Crossover Replicate, Bioequivalence Study of Naproxen 500 mg/ Esomeprazole 20 mg modified-release tablets (Antibio… Ended

2023-508621-27-00 healthy subjects 2 2024-03-05
A Randomized, Double-Blind, Placebo-Controlled Study of NIDO-361 in Patients with SBMA Ended

2023-507128-22-00 Spinal and Bulbar Muscular Atrophy 4 2024-03-01
A study to learn how different forms of study medicine tafamidis are taken up into the blood in healthy adults Ended

2023-509241-12-00 aransthyretin amyloid cardiomyopathy 3 2024-02-15
Dose-response characterization of VER-01 in the treatment of patients with chronic non-specific low back pain Ended

2023-507358-34-00 For the treatment of patients with chronic non-specific 4 2024-02-13
A SINGLE-CENTER, RANDOMIZED, PLACEBO-CONTROLLED STUDY TO ASSESS SAFETY, TOLERABILITY, AND PHARMACOKINETICS OF REPEAT DOSES OF ARM210 IN HEAL… Ended

2023-509086-20-00 Cardiac arrhythmias 3 2024-02-13
A Phase II/III Study of ABC008 to Determine Efficacy and Safety in IBM Ended

2022-501925-19-00 inclusion body myositis 10 2024-01-17
A randomized, multi-centre, double-blind, phase II clinical trial of dose finding of Montelukast in patients with erosive osteoarthritis of … Ended

2023-506137-30-00 Erosive osteoarthritis of the hands 4 2024-01-11
Efficacy, safety, PK, PD, and immunogenicity of BP16 in post-menopausal osteoporosis Ended

2023-503790-37-00 Post-Menopausal Osteoporosis 5 2024-01-09
Searching for the right dose of perineural dexmedetomidine for a interscalene plexus block. Ended

2023-506062-31-01 Patients scheduled for shoulder operations 11 2024-01-02
A Gene Transfer Therapy Study to Evaluate the Safety and Efficacy of Delandistrogene Moxeparvovec (SRP-9001) Following Imlifidase Infusion … Ended

2024-512624-11-00 Duchenne muscular dystrophy (DMD) 3 2023-12-15
Etude de dose de l’acide tranexamique dans la prothèse totale de hanche pour réduire la perte d’hémoglobine post-opératoire. Etude de phase … Ended

2022-502532-38-01 Arthropathy of Hip 4 2023-12-06
A Ph2 dose-finding study (MARS-17) to evaluate the efficacy and safety of GSK3858279 in adults with knee osteoarthritis pain. Ended

2022-502799-22-00 Knee osteoarthritis pain 4 2023-11-29
Tofacitinib in early active axial spondyloarthritis: a prospective, randomized, double-blind, placebo-controlled multicentre study - FASTLAN… Ended

2023-505050-18-00 Axial spondyloarthritis 6 2023-11-16
Study of efficacy and safety of secukinumab in participants with moderate-severe rotator cuff tendinopathy Ended

2022-502068-19-00 Moderate to severe rotator cuff tendinopathy 5 2023-11-16
A study to investigate the safety, tolerability and preliminary efficacy of NGI226 microparticles in patients with Achilles tendinopathy Ended

2022-500863-10-00 Achilles Tendinopathy 4 2023-10-18
Study of efficacy and safety of secukinumab in participants with moderate-severe rotator cuff tendinopathy Ended

2022-502080-38-00 Moderate to severe rotator cuff tendinopathy 5 2023-10-16
A proof-of-concept study with NVDX3, an osteogenic implant of human allogenic origin, in the treatment of low grade degenerative lumbar spon… Ended

2023-508471-37-00 Low grade degenerative lumbar spondylolisthesis by inte 7 2023-10-12
A Study of Retatrutide (LY3437943) Once Weekly in Participants Who Have Obesity or Overweight and Osteoarthritis of the Knee (TRIUMPH-4) Ended

2023-503660-17-00 Overweight 5 2023-10-09
Open label study to investigate patch adhesion of an Esflurbiprofen-containing patch in healthy volunteers Ended

2023-503609-12-00 patch adhesion trial with healthy subjects, therapeutic 3 2023-09-14
A randomized, parallel-group, double-blind, placebo-controlled, multicenter Phase III trial to evaluate efficacy and safety of secukinumab a… Ended

2022-501895-25-00 Polymyalgia Rheumatica 5 2023-09-13
Clonidine for postoperative pain management in patients undergoing spine surgery Ended

2023-505969-80-00 Degenerative spine diseases 4 2023-09-05
An Adaptive Phase 2a/2b Study of LY3871801 in Adult Participants With Rheumatoid Arthritis Ended

2022-502994-40-00 Rheumatoid Arthritis 4 2023-09-04
A randomized, placebo controlled, investigator and participant-blinded study, investigating safety, tolerability and efficacy of RHH646 in p… Ended

2022-502821-16-00 Knee Osteoarthritis 4 2023-09-01
A PHASE 1, RANDOMIZED, PLACEBO-CONTROLLED, SINGLE ASCENDING DOSE AND MULTIPLE ASCENDING DOSE ESCALATION STUDY OF THE SAFETY, TOLERABILITY, P… Ended

2023-503866-22-00 metabolic bone diseases 1 2023-08-11