Neoplasms

3,817 trials 1,526 recruiting

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A Worldwide Study Testing the New Drug Olverembatinib for Patients with Chronic Phase Chronic Myeloid Leukemia (POLARIS-2) Recruiting

2024-511495-32-00 Chronic Phase Chronic Myeloid Leukemia 5 2025-04-16
A phase II study assessing safety and efficacy of REPotrectinib in ROS1-positive non-small cell lung cancer patients with active brain mEtas… Recruiting

2023-508112-35-00 ROS1-positive non-small cell lung cancer (NSCLC) with a 4 2025-04-15
Transtympanic sodium thiosulfate to prevent cisplatin-related hearing loss, a randomized controlled multicenter phase III trial; The SOUND t… Recruiting

2023-503313-30-01 Head and Neck squamous cell carcinoma 5 2025-04-14
ReaLuP : Study on Re-treatment with Radiopharmaceutical Drug [177Lu]Lu-PSMA in Patients With Metastatic Castration-Resistant Prostate Cancer Recruiting

2024-512043-22-00 Metastatic prostate cancer 4 2025-04-11
A Phase 1b/2 study of arfolitixorin as part of 5-fluorouracil-based treatment regimens in the first-line treatment of metastatic colorectal … Recruiting

2024-516802-43-00 metastatic colorectal cancer 9 2025-04-09
A first-in-human clinical study to assess safety and tolerability of genetically modified T-cells in ROR1 positive tumors Recruiting

2024-512019-36-00 Adrenocortical carcinoma 1 2025-04-09
First-in-human Trial of DS-2243a in Participants with Advanced Solid Tumors Recruiting

2024-512058-11-00 Advanced Solid Tumor 1 2025-04-09
A Study to Understand the Optimization of the Cytokine Release Syndrome Profile for Glofitamab along with Gemcitabine Plus Oxaliplatin in Pa… Recruiting

2024-516791-15-00 Relapsed/Refractory Aggressive B-Cell Non-Hodgkin’s Lym 4 2025-04-08
Exploiting the synergistic effect of PARP inhibition with cisplatin and hyperthermia during interval cytoreductive surgery and HIPEC in ovar… Recruiting

2024-519170-39-00 fallopian tube cancer 9 2025-04-07
A trial to learn how well saruparib with camizestrant works and how safe it is in adults with advanced breast cancer that is hormone recepto… Recruiting

2023-504180-16-00 Advanced Breast Cancer 5 2025-04-07
Early Phase II Exploratory, Open-Label, Non-Randomized Study of Neoadjuvant Dostarlimab Monotherapy in Participants with Untreated T3-4N0-2 … Recruiting

2024-512499-36-00 pMMR/MSS resectable Colon Cancer 4 2025-04-03
Ivosidenib in participants with locally advanced or metastatic conventional chondrosarcoma untreated or previously treated with 1 or 2 syste… Recruiting

2023-508507-20-00 Locally advanced or metastatic conventional chondrosarc 5 2025-04-03
Oncolytic virus TILT-123 in combination with lymphocyte-depleting chemotherapy and TILs in the treatment of melanoma Recruiting

2024-514092-18-00 Melanoma 3 2025-03-31
A study in newly diagnosed glioblastoma patients that aims at testing the efficacy of Optune (Tumor Treating Fields), together with temozolo… Recruiting

2024-513550-30-00 Newly diagnosed Glioblastoma 5 2025-03-28
Clinical trial evaluating the efficacy of pemigatinib for the treatment of patients with solid tumours with an alteration of the gene FGFR Recruiting

2024-512729-10-00 Recurrent or metastatic solid cancer harboring a FGFR1, 4 2025-03-27
Precision cancer medicine in hard-to-treat rare cancers - repurposing drugs in earlier lines of treatment - MATRIX-RARE. Recruiting

2024-513779-42-02 Cancer 4 2025-03-27
Gemcitabine plus nab-PAclitaxel as switch maiNTEnance versus cONtinuation of modified FOLFIRINOX as first-line chemotherapy in patients with… Recruiting

2024-515214-41-00 advanced pancreatic cancer 5 2025-03-27
Study to Evaluate Adverse Events, Optimal Dose, and Change in Disease Activity, With Livmoniplimab in Combination With Budigalimab Plus Chem… Recruiting

2023-505773-32-00 Untreated Metastatic Non-Squamous Non-Small Cell Lung C 10 2025-03-25
First -in-Human Study of DS-3939a in Subjects with Advanced Solid Tumors Recruiting

2023-507937-14-00 Metastatic Solid Tumor 7 2025-03-25
Elacestrant versus Standard Endocrine Therapy in Women and Men with Node-positive, Estrogen Receptor-positive, HER2-negative, Early Breast C… Recruiting

2024-515445-42-00 Node-positive, Estrogen Receptor-positive, HER2-negativ 5 2025-03-24
[14C]-BMS986504 Mass Balance Study in Patients with Advanced Solid Tumors with Homozygous MTAP Deletion Recruiting

2024-515518-41-00 Advanced Solid Tumors 3 2025-03-24
Ivosidenib Plus Durvalumab and Gemcitabine/Cisplatin as First-Line Therapy in Participants with Locally Advanced or Metastatic Cholangiocarc… Recruiting

2024-514261-19-00 Locally advanced, unresectable or metastatic cholangioc 9 2025-03-24
68-Ga-FAPI-46 positron emission tomography (PET) to better visualise pancreatic and bile duct cancer. Recruiting

2024-516486-36-00 cholangiocarcinoma (bile duct cancer) 10 2025-03-24
A Phase 1a/b Study Investigating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Antitumor Activity of PRMT5 I… Recruiting

2024-515307-19-00 Advanced, or metastatic solid tumors with methylthioade 1 2025-03-24