Nutritional and Metabolic Diseases

441 trials 157 recruiting

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The effect of semaglutide therapy on hepatic fat content and on the acute response of liver fat to high-fat load Pending

2023-504988-16-00 Obesity 5
SGLT2 inhibitor or metformin as standard treatment in early type 2 diabetes (SMARTEST) Pending

2024-516228-33-00 Type 2 Diabetes 6
Prevention of heart disease in heart-healthy patients with diabetes based on a special parameter (NT-proBNP) Pending

2024-519051-28-01 Diabetes mellitus Type 2 6
A Study to Evaluate the Effect of RO7204239 on Insulin Sensitivity and Muscle Composition in Participants with Type 2 Diabetes Mellitus(T2DM… Pending

2025-521401-41-00 Type 2 Diabetes Mellitus (T2DM) and overweight or obesi 3
A research study on how well cagrilintide and CagriSema work in children and adolescents with excess body weight Pending

2023-509176-42-00 Obesity and T2D 11
Image-Verapamil SR in Adults with Type 1 Diabetes (Image-VER-A-T1D) Pending

2024-518554-17-00 type 1 diabetes mellitus 4
Cholesterol lowering with atorvastatine for the prevention of gallstones following bariatric surgery: an investigator- blinded randomised co… Pending

2025-524191-38-00 Gallstones (chole(cysto)lithiasis) following bariatric 6
Applying Mysimba in patients with weight regain after bariatric surgery Pending

2024-516645-39-01 Obesity 11
Efficacy and safety of a combined therapy in the symptomatic treatment of diabetic sensorimotor polyneuropathy - a prospective, randomized, … Pending

2025-521985-82-00 Diabetic sensorimotor polyneuropathy (DSPN) 4
Impact of GLP1-RAs on inflammation and endothelial biomarkerS in Type 2 diABetes meLlitus patiEnts: STABLE-GLP1 trial. Pending

2025-520802-37-00 Type 2 diabetes mellitus 6
Study to Evaluate the Efficacy and Safety of Lerodalcibep for the Reduction of Cholesterol in Children and Adolescents with Heterozygous Fam… Pending

2025-524214-28-00 Heterozygous Familial Hypercholesterolemia 5
Sodium-glucose cotransporter-2 inhibitors to stabilize coronary ather-osclerosis progression after acute myocardial infarction in women and … Pending

2025-523375-29-00 Myocardial Infarction 5
Evaluation of AG-181 in Subjects 18 to 69 Years of Age With Phenylketonuria Pending

2025-522630-31-00 Phenylketonuria 3
AMAZE 8: A research study investigating how well the medicine NNC0487-0111 compared to semaglutide helps people with excess body weight and … Recruiting

2024-520446-31-00 Participants with overweight or obesity, and type 2 dia 5 2026-05-27
A clinical study to evaluate the effects of RO7795068 in participants with obesity or overweight and type 2 diabetes Recruiting

2025-523106-32-00 Obesity or Overweight and Type 2 Diabetes 5 2026-05-25
A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which has Spread and Caused Significant Body Weight Lo… Recruiting

2025-522093-36-00 Cancer cachexia 10 2026-05-20
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin ( ENLIGHTEN-6 ) Recruiting

2025-523659-73-00 Obesity 5 2026-05-11
A clinical study to evaluate the effects of RO7795068 in participants with obesity or overweight without type 2 diabetes. Recruiting

2025-523104-71-00 Obesity or Overweight Without Type 2 Diabetes 5 2026-05-08
A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight (ENLIGHTEN-3) Recruiting

2025-523769-11-00 Overweight 5 2026-04-30
A multi-center evaluation of NGM120 in a randomized, double-blind, placebo-controlled study in participants with colorectal cancer who have … Recruiting

2025-521730-28-00 Colorectal Cancer with Cancer Cachexia 4 2026-03-30
Visugromab in Cachexia International Trial Recruiting

2025-523533-25-00 Cancer-associated Cachexia 10 2026-03-26
A first-in-human clinical trial using a gene therapy with patient’s own stem cells to treat early type 1 diabetes Recruiting

2025-521304-21-00 Type 1 diabetes 7 2026-03-13
A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRES… Recruiting

2025-522170-36-00 Diabetes Mellitus, Type 1 5 2026-02-03
Dose-Selection, Safety and Efficacy Study with Open-Label Extension of Choline Chloride for Injection in Adolescent and Adult Patients with … Recruiting

2024-519496-26-00 Intestinal Failure 10 2025-09-25