Phase I/II – Other

632 trials 274 recruiting

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HEAT-AML (Hydroxyurea-Enhanced Ara-C Treatment of Adult Acute Myeloid Leukaemia): A clinical study to assess whether addition of hydroxyurea… Ended

2023-509019-97-00 Newly diagnosed acute myeloid leukaemia (AML) in patien 2019-07-15
A Phase IB/II Study to determine efficacy and safety of Durvalumab + Paclitaxel and Durvalumab in Combination with Novel Oncology Therapies … Ended

2024-511646-40-00 First-line (1L) Stage IV Triple Negative Breast Cancer 2019-07-11
A prospective controlled trial to evaluate safety and efficacy of in vitro expanded recipient regulatory T cell therapy and tocilizumab toge… Ended

2024-513459-34-00 Kidney transplantation 2019-04-24
A Phase I/II Study of Paclitaxel plus Carboplatin and Durvalumab (MEDI4736) with or without Oleclumab (MEDI9447) for Previously Untreated Lo… Ended

2024-511850-34-00 Previously untreated locally recurrent inoperable or me 2019-01-02
Safety and Efficacy of Quizartinib in Children and Young Adults With Acute Myeloid Leukemia (AML), a Cancer of the Blood Ended

2023-510009-16-00 Acute Myeloid Leukemia 2018-12-04
Evaluation of the Efficacy and the Safety of FOLFIRINOX3 Bevacizumab Treatment in patients with colorectal cancer Ended

2024-515908-39-00 Patients with metastatic colorectal cancer 2018-10-29
Study to determine safety, efficacy and tolerability of Venetoclax in combination with Fludarabine, Citarabine and Idarubicin to achieve "th… Ended

2023-510517-26-00 Acute Myeloid Leukemia 2018-10-26
A study to evaluate the safety, the distribution and elimination of the compound in the body, and the effectiveness of Erdafitinib by itself… Ended

2023-510295-31-00 Metastatic or Locally Advanced Urothelial Cancer 2018-09-24
A clinical study to learn about the effects of a virus that transfers the gene for human Ornithine Transcarbamylase (OTC) in adults with lat… Ended

2022-501146-30-00 Ornithine transcarbamylase deficiency 2018-09-17
REGOMUNE : A phase I/II study of Regorafenib plus Avelumab in solid tumors Ended

2023-509500-15-00 Adult patients with advanced or metastatic solid tumors 2018-05-03
Multicenter, Dose-Escalation and Expansion Study of Combination Therapy with Venetoclax, Daratumumab and Dexamethasone (with and without Bor… Ended

2023-506110-43-00 Multiple Myeloma 2018-01-25
A study of TG4001 and avelumab cancer immunotherapies in advanced HPV-induced malignancies Ended

2024-515119-23-00 Phase Ib and Phase II part 1: HPV-16 positive recurrent 2017-08-29
Brentuximab vedotin+Adriamycin, vinblastine, and dacarbazine in pediatric patients with advanced stage newly diagnosed Hodgkin lymphoma Ended

2023-506415-18-00 Hodgkin lymphoma (HL) - Hodgkin lymphoma (HL), a neopla 2017-07-18
A study to test the safety and efficacy of the drug larotrectinib for the treatment of tumors with NTRK-fusion in children Ended

2022-502668-20-00 Solid tumors harboring NTRK fusion 2017-04-11
Phase I-II trial of sunitinib and/or nivolumab plus chemotherapy in advanced soft tissue and bone sarcomas Ended

2024-514776-40-00 Advanced soft tissue and bone sarcomas 2017-03-23
An open-label, multi-center rollover protocol for patients who have participated in a Novartis-sponsored ribociclib (LEE011) study and are c… Ended

2024-511125-61-00 Different types of advanced cancer 2017-03-08
A clinical trial to evaluate the safety and effectiveness of a combination of either AG-12or AG-221 tablets with azacitidine injections in p… Ended

2024-511722-31-00 Acute Myeloid Leukemia (AML) 2016-11-29
NEOadjuvant chemotherapy only compared with standard treatment for Locally Advanced Rectal cancer: a randomized phase II trial Ended

2024-517748-76-00 Rectum cancer 2016-11-14
Bosutinib in pediatric CML patients Ended

2023-504311-32-00 Chronic Myeloid Leukemia 2016-09-02
A study to decide what is the highest dose of CC-220 to take alone and with other standard of care treatments to assess the side effects, ef… Ended

2024-510799-19-00 Multiple Myeloma 2016-08-09
Phase I/II study to evaluate the efficacy and safety of PAZOPANIB in combination with TEMOZOLOMIDE as maintenance therapy in Glioblastoma pa… Ended

2024-510960-22-00 gliobastoma 2015-06-25
A trial to see the effects of increased doses of ACP-196 (the test drug) in subjects with Leukemia Ended

2023-509346-35-00 Richter's Syndrome 2015-05-26
A phase Ib/II, multicenter, study of the combination of LEE011 and BYL719 with letrozole in adult patients with advanced ER+ breast cancer Ended

2023-509511-84-00 Advanced HR+ breast cancer 2014-03-19
A dose finding study of LY3884961 in patients with Gaucher disease Halted

2022-500281-10-02 Type 1 Gaucher Disease (Peripheral/Non-neuronopathic Ma 2026-02-06