Phase I/II – Other

632 trials 274 recruiting

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Durability of protection after single immunisation with genetically attenuated Plasmodium falciparum ∆mei2 (GA2) sporozoites – a follow-up, … Ended

2024-513516-99-00 Falciparum malaria 2024-10-28
A multi-centre, randomised, single-blind Phase I/IIa study to evaluate the safety, tolerability and efficacy of a single topical dose of all… Ended

2024-518757-42-00 Difficult-to-heal venous leg ulcers 2024-10-28
A clinical gene therapy study with hematopoietic stem cells for the treatment, with single dose of Temferon, of patients suffering from meta… Ended

2024-512898-27-00 Patients with locally advanced/metastatic renal cell ca 2024-10-22
Study of the benefit of lenvatinib treatment in waiting list of liver transplantation after TACE failure in patients with hepatocellular car… Ended

2024-516408-40-00 Non-resectable hepatocellular carcinoma (HCC) 2024-10-14
A Phase I/IIa Study of ODX (OsteoDex) in Multiple Myeloma Ended

2024-516969-36-00 Multiple Myeloma 2024-09-16
A Phase 1/2 Study of AMG 193 in Combination with IDE397 in Subjects with Advanced MTAP-null Solid Tumors Ended

2023-504364-42-00 In Part 1, subjects with advanced MTAP-null solid tumor 2024-09-12
AML-NET : Acute Myeloid Leukemia treated with with NETrin Abs in combination with [AZACITIDINE + VENETOCLAX] Ended

2023-503408-10-00 Refractory Acute Myeloïd Leukemia 2024-09-08
A study to compare effectiveness and safety of a combination of vudalimab or pembrolizumab with chemotherapy in participants with advanced l… Ended

2023-509644-10-00 Advanced Non-small Cell Lung Cancer 2024-06-27
EPI-7386 in Combination with Enzalutamide versus Enzalutamide alone in Metastatic Castration-Resistant Prostate Cancer Ended

2023-509336-25-00 Metastatic castration-resistant prostate cancer 2024-06-12
A Safety, Efficacy and Pharmacokinetic Study of BTCT4465A (Mosunetuzumab) as a Single Agent and Combined with Atezolizumab in Non-Hodgkin's … Ended

2023-506820-10-00 B-Cell Malignancies 2024-06-11
A Phase 1/2, Open-Label, Multicenter Trial Investigating the Safety, Tolerability, and Preliminary Antineoplastic Activity of IPH6501 in Pat… Ended

2023-506976-28-00 Relapsed and/or Refractory CD20-expressing Non-Hodgkin 2024-05-16
A Phase I/II open label study to assess safety and preliminary evidence of a therapeutic effect of Azeliragon combined with conventional con… Ended

2024-512954-96-00 Glioblastoma 2024-05-14
A Phase 1 Study of INCB099280 in Combination With Adagrasib in Adults With Advanced Solid Tumors Harboring a KRASG12C Mutation Ended

2023-503223-26-00 Advanced Solid Tumors Harboring a KRASG12C Mutation 2024-05-07
A Phase 1/2a Dose-Escalating Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ARO-C3 in Adult Healthy V… Ended

2023-506690-36-00 complement-mediated renal disease 2024-05-06
A phase Ib/II single-arm, multicenter study of sacituzumab-govitecan, a TROP-2 targeting antibody linked with SN38, for patients with metast… Ended

2023-505257-40-00 metastatic esophagogastric adenocarcinoma (Stage IV) 2024-04-17
A trial to learn about a study drug (STAR-0215) in adults with hereditary angioedema Ended

2022-502953-32-01 Hereditary Angioedema (HAE) 2024-04-02
A Phase 1/2a Randomized, Double-Blind Placebo-controlled Study of Intra-articular Allocetra in Knee Osteoarthritis Ended

2023-508748-23-00 Knee osteoarthritis 2024-03-26
TACTIVE-U: An Umbrella Study to Investigate the Safety and Antitumor Activity of vepdegestrant (ARV-471) in Combination With Other Medicines… Ended

2023-507125-41-00 Advanced or Metastatic Breast Cancer 2024-03-25
A Study to Evaluate the Pharmacokinetics of Afamelanotide in Patients with Erythropoietic Protoporphyria (EPP). Ended

2023-507311-35-00 Erythropoietic Protoporphyria (EPP) 2024-03-07
A Phase 1b/2a, Dose Escalation Trial of Safety, Pharmacokinetic/Pharmacodynamic and Preliminary Clinical Activity of Briquilimab in Adult Pa… Ended

2023-507534-24-00 Chronic Inducible Urticaria 2024-03-06
A Study to Assess the Use of Methylone in the Treatment of Post-Traumatic Stress Disorder (PTSD) Ended

2023-505874-14-00 Post-Traumatic Stress Disorder (PTSD) 2024-01-16
[18F]-Fludarabine PET/MR Imaging for the Assessment of Newly-diagnosed Primary Central Nervous System (CNS) Lymphoma : a Pilot PET-MRI Study Ended

2024-512758-62-00 Patients with newly diagnosed primary central nervous s 2023-12-18
A Study to Evaluate Safety, Tolerability, and Clinical Activity of Forimtamig-Based Treatment Combinations in Participants with Relapsed or … Ended

2023-503689-21-00 Multiple myeloma (MM) 2023-12-05
Phase 1/2 Study of BDC-1001 as a Single Agent and in Combination with Nivolumab in Patients with Advanced HER2-Expressing Solid Tumors Ended

2024-518411-19-00 Advanced HER2-Expressing Solid Tumors. 2023-12-04