Phase I/II – Other

632 trials 274 recruiting

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Public title :A Phase 1b/2a trial to evaluate Invobenitug also known as Procizumab (PCZ; AK1967) in critical cardiovascular care. Halted

2024-518450-16-00 Cardiogenic shock due to Acute Coronary Syndrome, cardi 2025-06-13
NeoART – A phase Ib/II platform trial evaluating the safety and activity of neoadjuvant trastuzumab-deruxtecan containing combination therap… Halted

2024-518841-12-00 HER2 positive resectable esophagogastric adenocarcinoma 2025-03-25
Prospective pilot study, assessing imaging performance of 89Zirconium-labelled Girentuximab (89Zr-TLX250) PET-CT in Patients with HepatoCell… Halted

2023-508567-75-00 Gastro-Entero-Pancreatic Neuroendocrine Neoplasms 2025-01-29
PHASE IB/II STUDY TO EVALUATE SAFETY AND EFFICACY OF DEBIO 0123 AND SACITUZUMAB GOVITECAN IN TNBC OR HR+/HER2- ADVANCED/ METASTATIC BREAST C… Halted

2024-516322-60-00 TRIPLE-NEGATIVE OR HR+/HER2– ADVANCED/METASTATIC BREAST 2025-01-17
A phase 2 trial assessing Ifenprodil as a ReMyelinating repurpOsed Drug in Multiple Sclerosis – MODIF-MS Halted

2023-507874-42-00 Multiple sclerosis 2024-08-27
A trial to understand if AZD0486 is safe and helps in people with Relapsed or Refractory B-cell acute lymphoblastic leukemia (B-ALL) Halted

2023-505840-20-00 B-Cell Acute Lymphoblastic Leukaemia 2024-08-16
A study to evaluate novel immunotherapy combinations in participants with advanced non-small cell lung cancer (NSCLC) Halted

2023-508730-34-00 Non-small cell lung cancer (NSCLC): - Locally advanced 2024-07-10
Spartalizumab and low-dose PAzopanib in Refractory or Relapsed solid TumOrs of pediatric and adults SPARTO Halted

2024-513535-24-00 Refractory or Recurrent Solid Tumor 2022-05-02
A Phase I/II Combination Study of NMS-03305293 and Temozolomide in Adult Patients with Recurrent Glioblastoma Halted

2023-508318-41-00 Recurrent Glioblastoma 2021-09-30
A phase 1/2 study of subcutaneous blinatumomab administration in adults and adolescents with R/R and MRD+ B-ALL Halted

2023-506136-32-00 Relapsed or Refractory B cell Precursor Acute Lymphobla 2020-10-12
PD-L1 PET imaging during CAR T-cell therapy Ended

2024-518422-32-01 (Diffuse) Large B-cell Lymphoma 2026-05-20
Pharmacodynamics of a Fixed dose combination of 0.34% tropicamide and 2.5% phenylephrine hydrochloride, eye drop, Solution Ended

2024-517456-35-00 to obtain pre-operative mydriasis or for diagnostic pur 2025-10-08
A prospective, double-blinded, randomized, placebo-controlled phase 1/2a study to assess safety, tolerability, systemic exposure and prelimi… Ended

2024-517920-21-00 knee osteoarthritis 2025-08-19
A trial to learn how safe saruparib is and how well it works in people with advanced ovarian cancer Ended

2024-519044-32-00 Advanced/Recurrent Ovarian cancer 2025-08-06
A single-center pilot study to establish a novel hypoglycemic clamp procedure to assess the time to spontaneous recovery from hypoglycemia i… Ended

2025-520996-16-00 Type 2 Diabetes Mellitus 2025-07-02
A Study of Eciskafusp Alfa and Bacillus Calmette-Guérin (BCG) in Participants with High-Risk Bladder Cancer Unresponsive to BCG Treatment Ended

2024-515410-41-00 BCG-Unresponsive High-Risk Non-Muscle Invasive Bladder 2025-04-01
Phase 1/2 Study of Cobolimab plus Dostarlimab in Pediatric and Young Adult Participants with Newly Diagnosed and Relapsed/Refractory Tumors Ended

2024-511350-41-00 Relapsed/Refractory Tumors 2025-03-13
A phase I/II trial of D,L-MEthadone and mFOLFOX6 in treatment of advanced colorectal cancer (MEFOX) Ended

2024-519509-37-00 Patients with advanced, histologically confirmed, metas 2025-02-25
An Open-Label, Multicentre Phase 1b/2a Clinical Trial of BI-1607, an Fc-Engineered Monoclonal Antibody to FcγRIIB (CD32b), in Combination wi… Ended

2024-512670-10-00 Unresectable or Metastatic Melanoma 2025-02-13
Phase I/II study to determine the safety and efficacy of Ribociclib in combination with hormone therapy and hypofractionated radiotherapy in… Ended

2022-501527-24-00 breast cancer 2025-01-24
Evaluation of the safety and efficacy of Berubicin in the treatment of central nervous system lymphomas- BERUBICIN Ended

2024-516773-69-00 central nervous system (CNS) lymphomas 2024-11-18
A Study to assess the safety and potential use of GEH121224 (18F) Injection to visualise HER2-Receptor expression using PET imaging in patie… Ended

2023-507720-23-00 Metastatic breast cancer 2024-11-15
A multicentre clinical trial to assess the safety and tolerability of the combination of low-dose cytarabine or azacitidine, plus Venetoclax… Ended

2024-519275-26-00 Newly diagnosed acute myeloid leukemia patients aged eq 2024-11-15
The headache-inducing effects of sildenafil in men and women with episodic migraine without aura. Ended

2024-512014-17-02 Migraine without aura 2024-11-01