Phase I/II – Other

632 trials 274 recruiting

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A Study Evaluating the Efficacy and Safety of Neoadjuvant Immunotherapy Combinations in Patients with Surgically Resectable Hepatocellular C… Ended

2022-502840-11-00 Hepatocellular Carcinoma (Morpheus-Neo HCC) 2023-11-28
Study evaluating PSMA targeted radionuclide therapy in adult patients with metastatic clear cell renal cancer Ended

2022-502440-12-00 metastatic clear cell renal cancer with progressive dis 2023-11-16
A study to test the effect of Samuraciclib in Combination with Elacestrant in Participants with Hormone Receptor-positive (HR+) and Human Ep… Ended

2023-503846-30-00 Breast Cancer 2023-10-10
A clinical study of bemcentinib with standard of care chemoimmunotherapy in untreated advanced/metastatic non-small cell lung cancer patient… Ended

2024-511007-41-00 Untreated advanced or metastatic non-squamous non-small 2023-10-03
A study in healthy men to test whether itraconazole influences the amount of BI 1584862 in the blood Ended

2023-503542-31-00 Healthy volunteer trial 2023-09-29
An early-stage clinical study of a potential new medicine for patients with Netherton Syndrome Ended

2022-502853-32-00 Netherton's Syndrome 2023-08-18
ZN-c3 in Adult Participants With Metastatic Colorectal Cancer Ended

2022-502267-37-00 metastatic colorectal cancer 2023-07-17
Adipose-derived mesenchymal stem cells as local treatment of ulcerative colitis Ended

2024-518643-38-00 ulcerative colitis 2023-06-30
Study Evaluating the Effects of ARO-RAGE in Healthy Subjects and Patients with Inflammatory Lung Disease Ended

2023-509654-60-00 Inflammatory Lung Disease 2023-06-21
A Phase 1/2a Study Evaluating the Effects of ARO-MUC5AC Inhalation Solution in Healthy Subjects and Patients with Muco-Obstructive Lung Dise… Ended

2024-514809-67-00 Asthma and Chronic obstructive pulmonary disease 2023-06-21
A study in healthy male adult participants to assess how much test medicine (SAR443820) is taken up, broken down and removed by the body whe… Ended

2022-502534-23-00 amyotrophic lateral sclerosis (ALS) 2023-06-02
A Study Evaluating Safety and Therapeutic Activity of THOR-707 in Adult Subjects With Advanced or Metastatic Solid Tumors (THOR-707-101) Ended

2023-508422-95-00 Cancer 2023-05-25
A Phase 1/2, Umbrella Study of the Efficacy and Safety of Pembrolizumab plus Enfortumab vedotin +/- Investigational Agents in First-Line met… Ended

2023-506385-30-00 Advanced Urothelial Carcinoma 2023-05-22
KANDOVA An open multicenter study to evaluate the safety and tolerability of KAND567, in combination with carboplatin therapy, and to determ… Ended

2024-515572-13-00 Recurrent epithelial ovarian, fallopian tube, or primar 2023-04-26
A Phase Ib/II, Multi-Center, Open-Label Study to Evaluate the Safety/Tolerability, Pharmacokinetics, and Efficacy of GFH925 in Combination w… Ended

2022-501451-87-00 Previously Untreated Advanced NSCLC Harboring KRAS G12C 2023-03-31
Study of Elenestinib (BLU-263) in Advanced Systemic Mastocytosis (AdvSM) and and Other KIT Altered Hematologic Malignancies (AZURE) Ended

2023-510144-20-00 Advanced Systemic Mastocytosis 2023-03-29
A Safety and Antitumor Activity Trial of Immunoradiotherapy Combinations as a Treatment Option for Subjects with Metastatic Solid Tumors Ended

2023-508529-29-00 Metastatic Solid Malignant tumors 2023-03-08
Single arm phase II study of the efficacy and safety of the combination of Trastuzumab plus TUCAtinib plus viNorelbine in patients with HER2… Ended

2024-512590-27-00 Non-resectable locally advanced or metastatic HER2-posi 2023-03-08
Safety and Tolerability of AC01 in patients with heart failure Ended

2022-500347-20-00 Heart Failure 2023-02-23
Relatlimab + Nivolumab in Pediatric and Young Adult Lymphomas (RELATIVITY-069) Ended

2023-503715-14-00 Recurrent or Refractory Classical Hodgkin Lymphoma and 2022-12-29
Study to assess safety and identify dose of ribociclib in combination of temozolomide and topotecan (TOTEM) in patients (12 months – 21 year… Ended

2024-512095-35-00 Relapsed or refractory neuroblastoma and other solid tu 2022-12-27
Effect of mesenchymal stem cells on healing of foot ulcers in diabetes patients. A phase I pilot study. Ended

2023-505961-10-00 Diabetic foot ulcus 2022-12-15
A proof of concept study with NVD-003, an autologous osteogenic bone graft, in the treatment of congenital pseudarthrosis of the tibia in pe… Ended

2024-515478-29-00 Congenital pseudarthrosis of the tibia 2022-11-28
Study to evaluate the efficacy and safety of fedratinib in combination with CC-486 in patients suffering from myelofibrosis in acute phase. Ended

2024-519227-22-00 Myeloproliferative neoplasm in accelerated phase (MPN-A 2022-11-03