Therapeutic Exploratory (Phase II)

3,454 trials 1,368 recruiting

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Open-Label Study of Cabozantinib as 2nd Line Treatment in Subjects with Unresectable, Locally Advanced or Metastatic Renal Cell Carcinoma wi… Ended

2024-514479-16-00 Unresectable, Locally Advanced or Metastatic Renal Cell 2019-10-28
Precision Immuno-Oncology for advanced Non-small cell lung cancer patients with PD-1 ICI Resistance (PIONeeR clinical study) Ended

2024-515532-72-00 non small cell lung cancer 2019-10-08
A Clinical Trial Evaluating the Safety and Efficacy of Venetoclax in Combination with Atezolizumab and Obinutuzumab in Richter Transformatio… Ended

2024-516675-32-00 Richter syndrome of chronic lymphocytic leukemia 2019-10-08
Clinical trial with the drug lorlatinib in patients affected by a lymphoma that expresses the protein ALK, previously treated with ALK inhib… Ended

2025-520788-42-00 Anaplastic Large Cells Lymphoma (ALCL) ALK+ 2019-09-26
A study to learn about the effects and safety of obeticholic acid in combination with bezafibrate in participants with primary biliary chola… Ended

2024-513762-18-00 Primary Biliary Cholangitis (PBC) 2019-09-20
MRD-guided treatment with pembrolizumab and azacitidine in NPM1mut AML patients with an imminent hematological relapse Ended

2024-513956-14-00 Acute myeloid leukemia 2019-09-16
A Single-arm Study of Intrathecal SHP611 in Subjects with Metachromatic Leukodystrophy Ended

2024-514402-31-00 Late Metachromatic Leukodystrophy (MLD) 2019-09-09
PaTH Forward: A Phase 2, Multicenter, Randomized, Double-Blind, Placebo Controlled, Parallel Group Trial with an Open-Label Extension, Inves… Ended

2024-512967-29-00 Hypoparathyroidism (HP) in Adults 2019-09-03
A multicentre phase II, open-label, non-randomized study evaluating Platinum-Pemetrexed-Atezolizumab ( Bevacizumab) for patients with stage … Ended

2024-516201-23-00 Lung Cancer, NSCLC 2019-08-26
Effects of the appetite-inducing hormone ghrelin on decision making in healthy volunteers Ended

2024-517598-26-00 Gambling disorder 2019-08-26
Evaluation of Safety, Tolerability, and Changes in Biomarker and Clinical Outcome Assessments of Losmapimod for FSHD1 With Extension (FSHD) Ended

2024-512736-29-00 Facioscapulohumeral Muscular Dystrophy 1 (FSHD1) 2019-08-23
A Clinical Study of Cusatuzumab Plus Azacitidine in Patients With Newly Diagnosed Acute Myeloid Leukemia who are not Candidates for Intensiv… Ended

2024-513283-26-00 Acute Myeloid Leukemia 2019-08-20
A study comparing combination of Encorafenib + Binimetinib in Patients with BRAF V600-mutant Non-small Cell Lung Cancer. Ended

2024-515929-28-00 Non-small Cell Lung Cancer 2019-08-02
Open-label Follow-up Study of Soticlestat in Adults and Children with Developmental Epileptic Encephalopathies Ended

2022-502801-13-00 Epileptic Encephalopathies: Dravet Syndrome, Lennox Gas 2019-07-26
Trial evaluating the tolerance and safety of durvalumab - radiotherapy combination for treatment of cancers of the head and neck Ended

2024-513977-31-00 Untreated squamous cell carcinoma of the head and neck 2019-07-17
ERibulin in Advanced Solitary fibrous tumor, an ItaliaN sarcoma Group phase II study (ERASING) Ended

2024-517795-38-00 Advanced Solitary fibrous tumor 2019-06-26
A study to assess different investigational drugs for the treatment if hidradenitis suppurativa Ended

2023-509296-16-00 Moderate to severe hidradenitis suppurativa 2019-06-17
ABCSG 45: A clinical trial that examines whether the treatment with the medication olaparib in combination with the chemotherapy carboplatin… Ended

2024-512821-10-00 Early invasive triple negative breast cancer with posit 2019-06-17
Long-Term Safety and Efficacy of BMS-986165 in Subjects with Systemic Lupus Erythematosus Ended

2022-502444-13-00 Systemic Lupus Erythematosus 2019-05-28
Study of chemotherapy and immunotherapy for patients with lung cancer bounded in the thorax and potentially resectable Ended

2024-513731-24-00 Non-small cell lung cancer (NSCLC) 2019-05-14
A Phase II, single arm Study of avelumab in combination with Axitinib in Patients with unresectable/metastatic Gastrointestinal Stromal Tumo… Ended

2024-519176-95-00 Gastrointestinal Stromal Tumors (GIST) 2019-05-08
Evaluation of 64Cu-ATSM PET/CT as a predictor of response to neoadjuvant therapy in locally advanced rectal cancer (TEP-64Cu-ATSM-Rectum) Ended

2024-512855-19-00 Rectal adenocarcinoma 2019-04-30
A study on the safety, efficacy and immune response following sequential treatment with an anti-sense oligonucleotide against chronic Hepati… Ended

2024-512352-38-00 Hepatitis B, Chronic 2019-03-28
Study of IPH4102 alone or in combination with chemotherapy in patients with Advanced T-cell Lymphoma. Ended

2023-507777-18-00 Advanced T-Cell Lymphomas (TCL), i.e. Cutaneous T Cell 2019-03-19