Therapeutic Exploratory (Phase II)

3,454 trials 1,368 recruiting

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PROLONGSTEM is a long term follow-up study of all the patients who have received at least one infusion of HepaStem Ended

2022-500251-22-00 This study will include all patients having received at 2018-04-12
A Trial to Determine The Safety and Efficacy of CC-92480 Alone and When Combined With Dexamethasone in People Who Have Myeloma That is Not R… Ended

2023-508727-12-00 Relapsed and refractory multiple myeloma (RRMM) 2018-04-12
A study to find out if an investigational product, called LN-145 (also called tumor infiltrating lymphocytes) is an effective and safe treat… Ended

2024-510634-41-00 Recurrent, metastatic, or persistent Cervical Carcinoma 2018-02-22
KRd consolidation in myeloma patients with a positive PET-CT after standard first line treatment. A phase II study Ended

2024-511714-20-00 Multiple Myeloma 2018-01-30
An extension study to investigate how safe Vedolizumab is in child patients with Ulcerative Colitis or Crohn's Disease Ended

2023-507766-35-00 Ulcerative Colitis or Crohn's Disease 2018-01-09
Safety and efficacy of IMCgp100 versus Investigator’s Choice in advanced uveal melanoma Ended

2024-517290-24-00 Previously untreated advanced uveal melanoma (UM) 2017-12-19
Evaluation of 68GaNOTA-Anti-HER2 VHH1 uptake in brain metastasis of cancer patients Ended

2024-513997-23-00 Cancer patients with brain metastasis 2017-10-16
First-line immunotherapy using Wilms’ tumor protein 1 (WT1)-targeted dendritic cell vaccinations for malignant pleural mesothelioma Ended

2024-517970-35-00 Malignant Pleural Mesothelioma 2017-10-03
Study assessing the efficacy and safety of alpelisib plus fulvestrant or letrozole, based on prior endocrine therapy, in patients with PIK3C… Ended

2023-509167-24-00 Adult patients with PIK3CA mutant, HR-positive, HER2-ne 2017-10-02
Venglustat in Combination with Cerezyme in Adult Patients with Gaucher Disease Type 3 with venglustat monotherapy extension Ended

2023-508646-18-00 Gaucher disease type 3 2017-09-18
A prospective, multicenter, phase-II trial of ibrutinib plus venetoclax in physically fit patients with creatinine clearance ≥ 30 ml/min who… Ended

2023-510557-42-00 chronic lymphocytic leukemia 2017-07-10
Study of Nivolumab plus Ipilimumab, Ipilimumab or Cabazitaxel in Men with Metastatic Castration-Resistant Prostate Cancer Ended

2022-502909-15-00 Metastatic Castration-Resistant Prostate Cancer 2017-06-09
Randomized, multicentre phase II trial of the sequencing of Radium-223 and Docetaxel plus prednisone in symptomatic bone-only metastatic cas… Ended

2024-511660-89-00 metastatic castration resistant prostate cancer (mCRPC) 2017-06-09
A study to investigate the safety, tolerability, and pharmacokinetics/pharmacodynamics of Risdiplam in adult and pediatric patients with spi… Ended

2023-506739-14-00 Spinal Muscular Atrophy (SMA) 2017-05-12
Multicenter open-label, phase II trial, to evaluate the efficacy and safety of nal-IRI for progressing brain metastases in patients with HER… Ended

2024-514999-41-00 HER2 negative metastatic breast cancer (MBC) with nervo 2017-04-28
A Long-term Study to Evaluate Safety, Tolerability, and Efficacy of BMN 111 in Children with Achondroplasia Ended

2023-508754-26-00 Achondroplasia 2017-02-10
GIVE trial (Gazyvaro In combination with VEnetoclax in Elderly CLL) Ended

2024-511048-22-00 Chronic lymphocytic leukemia 2016-10-27
A Study to Evaluate the Long-Term Efficacy, Safety, and Tolerability of Repeated Administration of Upadacitinib (ABT-494) in Participants Wi… Ended

2024-510727-19-00 Crohn's Disease (CD) 2016-10-11
A Phase 2 Study of the Safety, Efficacy, and Pharmacodynamics of RTA 408 in the Treatment of Friedreich’s Ataxia Ended

2024-517436-22-00 Friedreich's ataxia 2016-07-21
Tepotinib Phase II study in advanced lung cancer harboring MET exon 14 (METex14) skipping alterations and MET amplification Ended

2024-512003-39-00 Lung Cancer 2016-07-18
"A study to learn how well the drug larotrectinib works in adults with different solid cancers with a change in the genes called NTRK fusion… Ended

2022-502667-38-00 Solid tumors harboring NTRK fusion 2016-06-20
Pembrolizumab (MK-3475) and pembrolizumab in combination with other investigational agents in high risk NMIBC patients unresponsive to BCG Ended

2022-502526-41-00 Non-Muscle Invasive Bladder Cancer (NMIBC) 2016-03-15
Clinical trial to compare the efficacy and tolerability of fulvestrant (FaslodexTM) 500mg with placebo versus fulvestrant (FaslodexTM) 500mg… Ended

2024-516132-10-00 Metastatic breast cancer 2016-02-05
A clinical trial to evaluate if CC-486 plus pembrolizumab works and is safe in patients with advanced or metastatic non-small cell lung canc… Ended

2024-513405-31-00 Second-line treatment of locally advanced or metastatic 2015-12-10