Therapeutic Exploratory (Phase II)

3,454 trials 1,368 recruiting

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A study of Iclusig (ponatinib), an oral kinase-inhibitor treatment administered, by standard dose or reduced doses, for patients with Philad… Ended

2024-514516-27-00 Chronic Phase Chronic Myeloid Leukemia 2015-12-01
A Trial to See the Effects of ACP-196 (the test drug) in Patients who have Mantle Cell Lymphoma Ended

2023-509352-34-00 Mantle Cell Lymphoma 2015-06-18
Multicenter trial with carfilzomib combined with lenalidomide or cyclophopshamide with or without autologous transplant in newly diagnosed m… Ended

2024-516630-35-01 NEWLY DIAGNOSED MULTIPLE MYELOMA (MM) PATIENTS ELEGIBLE 2015-01-12
A Phase II Study of MEDI4736 in Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer Ended

2024-512379-10-00 Locally Advanced or Metastatic Non-Small Cell Lung Canc 2014-09-23
BEACON: A randomised phase IIb trial of BEvACizumab added to Temozolomide ± IrinOtecan for children with refractory/relapsed Neuroblastoma Ended

2024-518931-12-00 Neuroblastoma 2014-05-15
A Study of Nivolumab and Nivolumab Combinations in Recurrent and Metastatic Colon Cancer Ended

2024-516004-42-01 MSI Negative Colorectal Cancer 2014-05-14
THIS IS A CLINICAL STUDY WHICH EVALUATES TREATMENT WITH CHLORAMBUCIL AND RITUXIMAB FOLLOWED BY RITUXIMAB GIVEN UNDER THE SKIN IN PATIENTS W… Ended

2023-507291-52-00 Extranodal Marginal Zone Lymphoma 2014-03-24
A trial to compare the levels of the active ingredient tacrolimus in the blood of patients before and after switching between the Prograf an… Ended

2024-513546-11-00 Prophylaxis of primary liver, kidney, heart, lung, and 2014-03-10
Clinical trial to evaluate the efficacy of intracoronary infusion of autologous bone marrow mononuclear in patients with dilated cardiomyopa… Ended

2024-516594-71-01 Idiopathic dilated cardiomyopathy 2013-12-12
A study, in which patients with late-stage lung cancer and changes in a gene called EGFR, will be first treated for 8 weeks with the drug er… Ended

2024-514268-18-00 Non-Small Cell Lung Cancer 2013-09-06
Clinical trial addressing the efficacy of first-line Chlamydophila psittaci-eradicating therapy with protracted administration of doxycyclin… Ended

2024-513426-29-00 Patients with newly diagnosed Ocular Adnexal Marginal Z 2013-03-19
Pediatric Lupus Trial of Belimumab Plus Background Standard Therapy (PLUTO) Ended

2024-512730-15-00 Systemic Lupus Erythematosus 2012-09-14
Placebo-controlled, multi-center study to evaluate catheter derived tests of Riociguat (BAY 63-2521) as well as safety and blood samples in … Ended

2023-507001-34-00 Patients symptomatic with pulmonary hypertension associ 2010-04-29
Impact of Multiple Doses of BAY63-2521 on Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Patients With Interstitial Lung Dis… Ended

2023-507526-17-00 "Patients with interstitial lung disease associated pul 2008-05-13
ME-401 combined with rituximab-bendamustine for high-risk and rituximab with a 1:1 randomization to ME-401 for low-risk follicular lymphoma … Ended

2022-501138-49-00 Follicular Lymphoma
Effect of Modafinil on military observational performance and residual capacity of the Dutch Air Assault Brigade: a field trial Ended

2023-509677-24-02 Healthy participants
EQU-001 as an Add-On Drug for People with Focal Seizures while on Medication Ended

2022-500302-18-00 Epilepsy
Exploratory study evaluating the relevance of [68Ga]Ga-PentixaFor for initial staging and detection of minimal residual disease in multiple … Ended

2022-500339-35-01 Multiple Myeloma
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of ABBV-916 in … Ended

2022-500691-59-00 Alzheimer's disease (AD)
A Phase 2 Trial Evaluating the Effects of Thiethylperazine as diagnostic tool and therapeutic agent in Patients Diagnosed with an Early Stag… Ended

2022-501137-23-00 Newly diagnosed early-to-mild dementia due to Alzheimer
Dapiglutide for the treatment of obesity (DREAM): a randomised, double-blind, placebo-controlled, investigator-initiated trial Ended

2022-501649-54-01 Obesity
Alcohol Use and Behavior in Young Adults Ended

2022-501809-13-01 Alcohol Use Disorder (AUD)
Magrolimab plus intensive chemotherapy in newly diagnosed “ELN intermediate or poor-risk” AML patients intended to undergo allogeneic stem … Ended

2022-502040-13-00 High-risk Myelodysplastic neoplasia
A Proof of Concept, Phase IIa, Open Label Study to Evaluate the Safety and Efficacy of Afamelanotide in Patients with Early Parkinson's Dise… Ended

2022-502207-30-01 Parkinson's Disease