Therapeutic Exploratory (Phase II)

3,454 trials 1,368 recruiting

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Study to evaluate the efficacy and safety of a local anesthetic used in flat foot or inguinal hernia interventions at two different concentr… Ended

2024-518179-76-00 Calcagno stop and inguinal hernia repair 2019-03-11
Efficacy of Olaparib in advanced cancers occurring in patients with germline mutations or somatic tumor mutations in homologous recombinatio… Ended

2024-518522-32-00 Basket tumors 2019-02-07
Phase II Open Labeled Trial of Disulfiram with Copper in Metastatic Breast Cancer Ended

2024-514665-19-00 metastatic breast cancer 2019-01-29
Efficacy and safety of tisagenlecleucel in adult patients with refractory or relapsed follicular lymphoma Ended

2023-508127-13-00 Adult patients with refractory or relapsed follicular l 2019-01-25
A study of full treatment-free remission in patients with chronic myeloid leukemia Ended

2024-516122-66-00 Chronic myeloid leukemia 2019-01-18
A study to assess the efficacy and safety of bb2121 in people who have Myeloma that is not responsive after treatment or who had Myeloma whi… Ended

2023-505183-10-00 Relapsed and refractory multiple myeloma (RRMM), multip 2019-01-04
A Study of Pembrolizumab Combination Therapy for Advanced Non-Small Cell Lung Cancer Ended

2022-500990-16-00 Stage IV non-small cell lung cancer 2018-12-19
A clinical study to investigate if the investigational products, called LN-144 and LN-145 (also known as Tumour Infiltrating Lymphocytes), a… Ended

2024-510779-39-00 Neoplasm 2018-12-19
Olaparib Monotherapy in HRRm or HRD Positive Cancer Ended

2022-500797-34-00 Treatment of participants with positive cancer for HRRm 2018-12-17
Study of efficacy and safety of asciminib in addition to imatinib in CML-CP patients without a deep level or response on imatinib Ended

2024-515040-23-00 Chronic Myelogenous Leukemia in chronic phase (CML-CP), 2018-11-26
First line treatment with osimertinib in non-small cell lung cancer, coupled with studies on biological samples. Ended

2024-513881-20-00 EGFR-mutated non-small cell lung cancer 2018-11-19
A Phase II trial find out the effectiveness and safety of durvalumab combined with olaparib compared to durvalumab alone, in treating patien… Ended

2024-512769-16-00 Stage IV Non Small Cell Lung Cancer whose tumors lack E 2018-11-14
Clinical Trial conduct to investigate if Daratumumab therapy for multiple myeloma patients with minimal residual disease (MRD) reappearance … Ended

2024-518400-50-00 Multiple Myeloma and Minimal Residual Disease 2018-11-14
A Phase 2 Multicenter Study of Axicabtagene Ciloleucel in Subjects With Relapsed/Refractory Indolent Non-Hodgkin Lymphoma Ended

2023-505169-10-00 Follicular Lymphoma, Marginal Zone Lymphoma, Indolent N 2018-09-07
Rituximab, bendamustine and cytarabine followed by venetoclax (V-RBAC) in high-risk elderly patients with mantle cell lymphoma (MCL) Ended

2024-511533-35-00 Mantle Cell Lymphoma 2018-09-03
A Study to Assess Tiragolumab in Combination With Atezolizumab in Chemotherapy-Naïve Patients With Locally Advanced or Metastatic Non-Small … Ended

2023-508083-30-00 Non-small cell lung cancer (NSCLC) 2018-07-19
Study of Brexucabtagene Autoleucel (KTE-X19) in Participants With Relapsed/Refractory Mantle Cell Lymphoma (Cohort 3) (ZUMA-2) Ended

2023-506641-35-00 Relapsed/Refractory Mantle Cell Lymphoma 2018-07-09
A Biomarker-Directed Phase 2 Trial of SY-1425, a Selective Retinoic Acid Receptor Alpha Agonist, in Adult Patients with Acute Myeloid Leukem… Ended

2024-516281-11-00 Acute Myeloid Leukemia (AML) Myelodysplastic Syndrome 2018-06-06
Blinatumomab added to prephase and consolidation therapy in precursor B-acute lymphoblastic leukemia in adults. Ended

2024-511050-44-00 Precursor B-acute lymphoblastic leukemia 2018-05-16
FFCD 1605- OPTIPRIME: A phase II study evaluating FOLFOX + panitumumab according to a ‘stop-and-go’ strategy with a reintroduction loop afte… Ended

2024-518740-20-00 metastatic colorectal adenocarcinoma 2018-04-26
MULTICENTER RANDOMIZED PHASE II STUDY COMPARING THE EFFECTIVENESS AND TOLERANCE OF AVELUMAB VERSUS STANDARD 2nd LINE TREATMENT CHEMOTHERAPY … Ended

2024-517362-41-00 COLORECTAL METASTATIC CANCER WITH MICROSATELLITE INSTAB 2018-04-24
A study to investigate the efficacy of ramucirumab in combination with dacarbazine in patients with progressive well-differentiated metastat… Ended

2024-515045-42-00 Progressive well-differentiated metastatic neuroendocri 2018-04-23
Organ preservation in locally advanced rectal cancer by radiochemotherapy followed by consolidation chemotherapy. A prospective phase II pil… Ended

2024-517928-19-00 Male and female patients with histologically confirmed 2018-04-17
A Phase 2 Study combining BGB-3111 with Obinutuzumab compared with Obinutuzumab Monotherapy in Relapsed/Refractory Follicular Lymphoma Ended

2023-509975-17-00 Relapsed/Refractory Follicular Lymphoma 2018-04-12