Phase I/II – First Administration

443 trials 187 recruiting

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A Study of Zenocutuzumab (MCLA-128) in Patients With Solid Tumors Harboring an NRG1 Fusion (eNRGy) Recruiting

2024-512358-78-00 Solid Tumors 2015-01-20
Phase 1/2A Study of OTP-01, a Dual Paratopic PD-1/VEGFR2 Antibody, in Patients with Advanced Solid Tumors Recruiting

2025-524111-37-00 advanced solid tumors 2026-04-28
Study of ART6043 in Advanced/Metastatic Solid Tumors Patients Recruiting

2023-509220-17-00 Metastatic solid tumors 2026-04-10
The STELLAR trial: Fluorescence-guided surgery in laryngeal- and hypopharyngeal cancer: a feasibility trial Recruiting

2024-519750-36-00 Squamous cell carcinoma of the larynx and hypopharynx 2026-03-31
A phase I/IIa, dose-finding study to assess the safety and immunogenicity of an Orf virus-based COVID-19 vaccine booster (Prime-2-CoV_Beta) … Recruiting

2024-511266-36-00 The clinical trial itself does not investigate a medica 2026-03-26
An early phase trial of RPTR-1-201 in Advanced Solid Tumors Recruiting

2025-524010-28-00 Advanced Solid Tumor 2026-03-20
(Title in lay language): A trial to learn how safe AZD0516 is and how well it works with and without other cancer treatments in adults with … Recruiting

2024-520026-11-00 Metastatic Prostate Cancer 2026-03-19
A Clinical Trial to Test if the Investigational Drug BNT329 is Safe and Potentially Beneficial for People With Advanced Solid Tumors Known t… Recruiting

2025-522613-26-00 Advanced Solid Cancers 2026-03-13
A Phase 1 Study of Fentanyl Vaccine Recruiting

2025-524277-16-00 Opioid induced respiratory depression 2026-02-26
A Phase 1/2 Open Label Cohort Comparative Study Evaluating the Efficacy and the safety of Gene Therapy of the Sickle Cell Disease by Transpl… Recruiting

2025-521257-17-00 SCD severe patients 2026-02-25
A Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Anti-tumour Activity of IPN01203 in Adult… Recruiting

2025-522184-15-00 Advanced Solid Tumor, Metastatic Solid Tumor 2026-02-18
A Clinical Trial to learn about the effects of TLN-372 when given Alone and in Combination with Other Anti-Tumor Agents in people with Advan… Recruiting

2025-523086-22-00 Locally advanced or metastatic solid tumors 2026-02-18
A Phase 1/2 clinical trial of DT-7012 as monotherapy and in combination with an immune checkpoint inhibitor in participants with selected ad… Recruiting

2025-523758-15-00 Cancer 2026-02-11
A study to assess the safety, tolerability, pharmacokinetic, pharmacodynamic, immunogenicity and antitumour activity of IPN60300 in adults w… Recruiting

2025-522139-33-00 Advanced or metastatic solid tumours 2026-02-10
A first-in-human study to determine a safe dose of the drug TD001 to treat patients with metastatic prostate cancer that expresses the PSMA … Recruiting

2025-523273-41-00 Metastatic castration-resistant prostate cancer 2026-01-30
A Phase 1-2 Master Protocol to Study Intravenous ATTR-01 in Adult Participants with Select Epithelial Solid Tumours Under Multiple Sub-proto… Recruiting

2024-516722-59-00 Select Epithelial Solid Tumours 2026-01-23
A Study to test ALE.P03 in Adult Patients with Selected Advanced or Metastatic CLDN1+ Solid Tumors Recruiting

2025-521441-24-00 Advanced or Metastatic Solid Tumors 2026-01-19
A Clinical study of MK-4716 in people with certain solid tumors (MK-4716-001) Recruiting

2025-522495-84-00 Cancer – Solid Tumors : 1L NSCLC and all other advanced 2026-01-14
A trial to learn how safe AZD4512 is and how it works in the bodies of people with B-cell acute lymphoblastic leukemia (B-ALL) Recruiting

2025-522372-93-00 B-cell acute lymphoblastic leukemia (B-ALL) 2026-01-13
A trial to learn how safe AZD4360 is, how well it works, and how it moves throughout the body over time in adults with advanced solid tumors Recruiting

2024-518281-27-00 Gastric Cancer, Gastroesophageal Junction Cancer, Bilia 2026-01-09
A trial to learn how safe AZD4512 is with and without other cancer drugs and how it works in the bodies of people with B-cell non-Hodgkin ly… Recruiting

2025-522371-29-00 Non-Hodgkin lymphoma (NHL) 2025-12-19
A Phase 1/2a, First-in-human, Study of BMS-986517 in Participants with Advanced Solid Tumors Recruiting

2025-522203-23-00 Advanced Solid Tumors 2025-12-18
A Study to Test the Safety and Effects of a New Cancer Drug (TUB-030) in Patients with Advanced Solid Tumors Recruiting

2025-522517-35-00 Patients with advanced/metastatic tumors with head and 2025-12-16
QUADvance: Advancing Allogeneic Quad-CAR01-T Therapy in Hard-to-Treat B-Cell Cancers Recruiting

2025-521735-36-00 Relapsed/refractory B-cell non-Hodgkin lymphoma (R/R B- 2025-12-15